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Taf1a Gene Detail
Summary
  • Symbol
    Taf1a
  • Name
    TATA-box binding protein associated factor, RNA polymerase I, A
  • Synonyms
    mTAFI48
  • Feature Type
    protein coding gene
  • IDs
    MGI:109578
    NCBI Gene: 21339
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:183170325-183191020 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 1, Syntenic
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    77 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_109578
 protein coding gene Chr1:183170225-183195776 (+)
129S1/SvImJ MGP_129S1SvImJ_G0016904
 protein coding gene Chr1:190049799-190072786 (+)
A/J MGP_AJ_G0016883
 protein coding gene Chr1:182279657-182300997 (+)
AKR/J MGP_AKRJ_G0016848
 protein coding gene Chr1:187702202-187723350 (+)
BALB/cJ MGP_BALBcJ_G0016841
 protein coding gene Chr1:182920539-182940923 (+)
C3H/HeJ MGP_C3HHeJ_G0016665
 protein coding gene Chr1:188497324-188521133 (+)
C57BL/6NJ MGP_C57BL6NJ_G0017304
 protein coding gene Chr1:196138140-196161297 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0015011
 protein coding gene Chr1:173334223-173354724 (+)
CAST/EiJ MGP_CASTEiJ_G0016248
 protein coding gene Chr1:187889462-187911301 (+)
CBA/J MGP_CBAJ_G0016639
 protein coding gene Chr1:203453084-203481280 (+)
DBA/2J MGP_DBA2J_G0016745
 protein coding gene Chr1:181061284-181081285 (+)
FVB/NJ MGP_FVBNJ_G0016741
 protein coding gene Chr1:179193631-179213547 (+)
LP/J MGP_LPJ_G0016820
 protein coding gene Chr1:191228412-191254117 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0016773
 protein coding gene Chr1:210387485-210410714 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0017341
 protein coding gene Chr1:187527121-187549585 (+)
PWK/PhJ MGP_PWKPhJ_G0016035
 protein coding gene Chr1:180265071-180285538 (+)
SPRET/EiJ MGP_SPRETEiJ_G0015811
 protein coding gene Chr1:186488324-186510376 (+)
WSB/EiJ MGP_WSBEiJ_G0016310
 protein coding gene Chr1:187701264-187721733 (+)



Homology
more
  • Human Ortholog
    TAF1A, TATA-box binding protein associated factor, RNA polymerase I subunit A
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TAF1A, TATA-box binding protein associated factor, RNA polymerase I subunit A
  • Synonyms
    MGC:17061, RAFI48, SL1, TAFI48
  • Links
    NCBI Gene ID: 9015
    neXtProt AC: NX_Q15573
    UniProt: Q15573

  • Chr Location
    1q41; chr1:222554105-222589933 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    8 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
    13
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    45
  • Literature Summary
    1
Sequences &
Gene Models
less
  • All Sequences
    45
  • RefSeq
    11
  • UniProt
    4
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000072258 Ensembl Gene Model | MGI Sequence Detail 20696 C57BL/6J ±  kb
transcript ENSMUST00000192076 Ensembl | MGI Sequence Detail 2384 Not Applicable  
polypeptide ENSMUSP00000142213 Ensembl | MGI Sequence Detail 453 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    4 Sequences
  • Protein Ontology
    PR:000016020 TATA box-binding protein-associated factor RNA polymerase I subunit A
    (term hierarchy)
  • InterPro Domains
    IPR039495 TATA box-binding protein-associated factor RNA polymerase I subunit A
    IPR016629 TATA box-binding protein-associated factor RNA polymerase I subunit A, chordata
Molecular
Reagents
less
  • All nucleic 46
    cDNA 46

    Microarray probesets 3
Other
Accession IDs
less
MGD-MRK-39577
References
more
  • Summaries
    All 33
    Developmental Gene Expression 1
    Gene Ontology 6
    Phenotypes 8
  • Earliest
    J:39012 Heix J, et al., Cloning of murine RNA polymerase I-specific TAF factors: conserved interactions between the subunits of the species-specific transcription initiation factor TIF-IB/SL1. Proc Natl Acad Sci U S A. 1997 Mar 4;94(5):1733-8
  • Latest
    J:245730 Bardot P, et al., The TAF10-containing TFIID and SAGA transcriptional complexes are dispensable for early somitogenesis in the mouse embryo. Development. 2017 Oct 15;144(20):3808-3818
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory