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Oaz2 Gene Detail
Summary
  • Symbol
    Oaz2
  • Name
    ornithine decarboxylase antizyme 2
  • Synonyms
    antizyme 2, AZ2, AZ-2, Oaz2-ps, Sez15
  • Feature Type
    protein coding gene
  • IDs
    MGI:109492
    NCBI Gene: 18247
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:65583830-65597582 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 9, 35.45 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    69 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_109492
protein coding gene Chr9:65575283-65597582 (+)
129S1/SvImJ MGP_129S1SvImJ_G0034965
protein coding gene Chr9:65443280-65468196 (+)
A/J MGP_AJ_G0034945
protein coding gene Chr9:63216876-63239077 (+)
AKR/J MGP_AKRJ_G0034875
protein coding gene Chr9:64719440-64742460 (+)
BALB/cJ MGP_BALBcJ_G0034938
protein coding gene Chr9:62934319-62956922 (+)
C3H/HeJ MGP_C3HHeJ_G0034648
protein coding gene Chr9:65251825-65275974 (+)
C57BL/6NJ MGP_C57BL6NJ_G0035457
protein coding gene Chr9:67212273-67242834 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0032368
protein coding gene Chr9:62858305-62880536 (+)
CAST/EiJ MGP_CASTEiJ_G0033969
protein coding gene Chr9:65421845-65450359 (+)
CBA/J MGP_CBAJ_G0034619
protein coding gene Chr9:69569889-69595730 (+)
DBA/2J MGP_DBA2J_G0034778
protein coding gene Chr9:62981779-63012126 (+)
FVB/NJ MGP_FVBNJ_G0034720
protein coding gene Chr9:62308863-62346681 (+)
LP/J MGP_LPJ_G0034861
protein coding gene Chr9:65690878-65714872 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0034762
protein coding gene Chr9:70789231-70826737 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0035479
protein coding gene Chr9:64822284-64844953 (+)
PWK/PhJ MGP_PWKPhJ_G0033673
protein coding gene Chr9:63185363-63208502 (+)
SPRET/EiJ MGP_SPRETEiJ_G0033507
protein coding gene Chr9:65110611-65135021 (+)
WSB/EiJ MGP_WSBEiJ_G0034082
protein coding gene Chr9:64719715-64745618 (+)



Homology
more
  • Human Ortholog
    OAZ2, ornithine decarboxylase antizyme 2
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    OAZ2, ornithine decarboxylase antizyme 2
  • Synonyms
    AZ2
  • Links
    NCBI Gene ID: 4947
    neXtProt AC: NX_O95190
    UniProt: O95190

  • Chr Location
    15q22.31; chr15:64687573-64703281 (-)  GRCh38

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotypes from 1 allele in 1 genetic background
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 18247 NCBI Gene Model | MGI Sequence Detail 13753 C57BL/6J ±  kb
    transcript NM_010952 RefSeq | MGI Sequence Detail 1861 C57BL/6  
    polypeptide O08608 UniProt | EBI | MGI Sequence Detail 189 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 16
      cDNA 13
      Primer pair 2
      Other 1

      Microarray probesets 4
    Other
    Accession IDs
    less
    MGD-MRK-39491
    References
    more
    • Summaries
      All 40
      Developmental Gene Expression 2
      Gene Ontology 8
      Phenotypes 10
    • Earliest
      J:31864 Kajiwara K, et al., Molecular characterization of seizure-related genes isolated by differential screening. Biochem Biophys Res Commun. 1996 Feb 27;219(3):795-9
    • Latest
      J:211327 Ramos-Molina B, et al., Structural and degradative aspects of ornithine decarboxylase antizyme inhibitor 2. FEBS Open Bio. 2014;4:510-21

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    last database update
    04/02/2024
    MGI 6.23
    The Jackson Laboratory