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Vcf1 Gene Detail
Summary
  • Symbol
    Vcf1
  • Name
    VCP nuclear cofactor family member 1
  • Synonyms
    D11Wsu99e, Fam104a
  • Feature Type
    protein coding gene
  • IDs
    MGI:106351
    NCBI Gene: 28081
  • Alliance
    gene page
  • Transcription Start Sites
    9 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:113552145-113574981 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 79.12 cM
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    202 from dbSNP Build 142
  • Strain Annotations
    15
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_106351
 protein coding gene Chr11:113552145-113574988 (-)
129S1/SvImJ no annotation
A/J MGP_AJ_G0019320
 protein coding gene Chr11:112428972-112451850 (-)
AKR/J MGP_AKRJ_G0018132
 protein coding gene Chr11:44888850-44890734 (-)
BALB/cJ no annotation
C3H/HeJ no annotation
C57BL/6NJ MGP_C57BL6NJ_G0019744
 protein coding gene Chr11:121014067-121039222 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0017367
 protein coding gene Chr11:109504828-109528285 (-)
CAST/EiJ MGP_CASTEiJ_G0018656
 protein coding gene Chr11:117359807-117385084 (-)
CBA/J MGP_CBAJ_G0019072
 protein coding gene Chr11:125948075-125971101 (-)
DBA/2J MGP_DBA2J_G0019184
 protein coding gene Chr11:111865606-111888481 (-)
FVB/NJ MGP_FVBNJ_G0019175
 protein coding gene Chr11:111342811-111366883 (-)
LP/J MGP_LPJ_G0019254
 protein coding gene Chr11:117925678-117952584 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0019206
 protein coding gene Chr11:125098139-125122608 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0019781
 protein coding gene Chr11:116388891-116413599 (-)
PWK/PhJ MGP_PWKPhJ_G0018421
 protein coding gene Chr11:113076172-113099702 (-)
SPRET/EiJ MGP_SPRETEiJ_G0018213
 protein coding gene Chr11:116201011-116223040 (-)
WSB/EiJ MGP_WSBEiJ_G0018708
 protein coding gene Chr11:116350540-116374446 (-)



Homology
more
  • Human Ortholog
    VCF1, VCP nuclear cofactor family member 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    VCF1, VCP nuclear cofactor family member 1
  • Synonyms
    FAM104A
  • Links
    NCBI Gene ID: 84923
    neXtProt AC: NX_Q969W3
    UniProt: Q969W3

  • Chr Location
    17q25.1; chr17:73207353-73236753 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    8 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    712
  • Tissues
    2
  • cDNA Data
    16
  • Literature Summary
    1
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000041629 Ensembl Gene Model | MGI Sequence Detail 22837 C57BL/6J ±  kb
    transcript ENSMUST00000120194 Ensembl | MGI Sequence Detail 2619 Not Applicable  
    polypeptide ENSMUSP00000113652 Ensembl | MGI Sequence Detail 185 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      5 Sequences
    • InterPro Domains
      IPR029222 VCF1/2-like
    Molecular
    Reagents
    less
    • All nucleic 17
      cDNA 16
      Primer pair 1

      Microarray probesets 6
    Other
    Accession IDs
    less
    MGD-MRK-34043
    References
    more
    • Summaries
      All 29
      Developmental Gene Expression 1
      Phenotypes 8
    • Earliest
      J:50869 Ko MSH, et al., Genome-wide mapping of unselected transcripts from extraembryonic tissue of 7.5-day mouse embryos reveals enrichment in the t-complex and under-representation on the X chromosome. Hum Mol Genet. 1998 Nov;7(12):1967-78
    • Latest
      J:274872 Ingham NJ, et al., Mouse screen reveals multiple new genes underlying mouse and human hearing loss. PLoS Biol. 2019 Apr;17(4):e3000194
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    04/09/2024
    MGI 6.23     		The Jackson Laboratory