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Tes Gene Detail
Summary
  • Symbol
    Tes
  • Name
    testin LIM domain protein
  • Synonyms
    D6Ertd352e, Tes1, Tes2, testin, testin2
  • Feature Type
    protein coding gene
  • IDs
    MGI:105081
    NCBI Gene: 21753
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr6:17065148-17105824 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 6, 7.67 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    473 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_105081
 protein coding gene Chr6:17065148-17105827 (+)
129S1/SvImJ MGP_129S1SvImJ_G0030467
 protein coding gene Chr6:14286371-14326610 (+)
A/J MGP_AJ_G0030440
 protein coding gene Chr6:13709497-13749237 (+)
AKR/J MGP_AKRJ_G0030367
 protein coding gene Chr6:14189629-14231275 (+)
BALB/cJ MGP_BALBcJ_G0030449
 protein coding gene Chr6:13800630-13840409 (+)
C3H/HeJ MGP_C3HHeJ_G0030163
 protein coding gene Chr6:14054079-14094663 (+)
C57BL/6NJ MGP_C57BL6NJ_G0030904
 protein coding gene Chr6:14746892-14786695 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0028115
 protein coding gene Chr6:12685815-12724172 (+)
CAST/EiJ MGP_CASTEiJ_G0029565
 protein coding gene Chr6:13962723-14003803 (+)
CBA/J MGP_CBAJ_G0030141
 protein coding gene Chr6:15212275-15252416 (+)
DBA/2J MGP_DBA2J_G0030285
 protein coding gene Chr6:13634939-13674732 (+)
FVB/NJ MGP_FVBNJ_G0030239
 protein coding gene Chr6:13481681-13521464 (+)
LP/J MGP_LPJ_G0030372
 protein coding gene Chr6:14366613-14415191 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0030275
 protein coding gene Chr6:16411781-16451587 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0030934
 protein coding gene Chr6:14071182-14110990 (+)
PWK/PhJ MGP_PWKPhJ_G0029279
 protein coding gene Chr6:13286281-13327241 (+)
SPRET/EiJ MGP_SPRETEiJ_G0029115
 protein coding gene Chr6:13917676-13962055 (+)
WSB/EiJ MGP_WSBEiJ_G0029641
 protein coding gene Chr6:14001908-14041680 (+)



Homology
more
  • Human Ortholog
    TES, testin LIM domain protein
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TES, testin LIM domain protein
  • Synonyms
    TESS, TESS-2
  • Links
    NCBI Gene ID: 26136
    neXtProt AC: NX_Q9UGI8
    UniProt: Q9UGI8

  • Chr Location
    7q31.2; chr7:116210506-116258783 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotypes from 2 alleles in 2 genetic backgrounds
    2 images
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Homozygous and heterozygous null mice display small forestomachs with thickened epithelium and increased tumor incidence and malignancy.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    11
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    1117
  • Tissues
    191
  • cDNA Data
    15
  • Literature Summary
    12
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 21753 NCBI Gene Model | MGI Sequence Detail 40677 C57BL/6J ±  kb
    transcript NM_207176 RefSeq | MGI Sequence Detail 2442 Not Specified  
    polypeptide P47226 UniProt | EBI | MGI Sequence Detail 423 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 23
      cDNA 15
      Primer pair 7
      Other 1

      Microarray probesets 5
    Other
    Accession IDs
    less
    MGD-MRK-32121, MGI:1196300
    References
    more
    • Summaries
      All 48
      Developmental Gene Expression 12
      Gene Ontology 4
      Phenotypes 10
    • Earliest
      J:2278 Porteus MH, et al., Isolation and characterization of a library of cDNA clones that are preferentially expressed in the embryonic telencephalon. Brain Res Mol Brain Res. 1992 Jan;12(1-3):7-22
    • Latest
      J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022;
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    04/09/2024
    MGI 6.23     		The Jackson Laboratory