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mea Gene Detail
Summary
  • Symbol
    mea
  • Name
    meander tail
  • Feature Type
    heritable phenotypic marker
  • IDs
    MGI:96956
    NCBI Gene: 17255
  • Alliance
    gene page
Location &
Maps
more
  • Sequence Map
    Genome coordinates not available from the current reference assembly.
  • Genetic Map
    Chromosome 4, Syntenic
  • Mapping Data
    5 experiments
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    22 phenotypes from 3 alleles in 4 genetic backgrounds
    2 images
    16 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for this mutation display variable severity of tail kinks, variable ankylosis or fusion of the caudal vertebrae, and abnormal anterior cerebellum morphology including loss of granule cells and ectopic Purkinje cells.
Sequences &
Gene Models
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Other
Accession IDs
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MGD-MRK-12182
References
more
  • Summaries
    All 17
    Phenotypes 16
  • Earliest
    J:5951 Hollander WF, et al., Meander tail: a recessive mutant located in chromosome 4 of the mouse. J Hered. 1977 Nov-Dec;68(6):403-6
  • Latest
    J:109119 Manzini MC, et al., The stop signal revised: immature cerebellar granule neurons in the external germinal layer arrest pontine mossy fiber growth. J Neurosci. 2006 May 31;26(22):6040-51
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory