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Aft Gene Detail
Summary
  • Symbol
    Aft
  • Name
    abnormal feet and tail
  • Feature Type
    heritable phenotypic marker
  • IDs
    MGI:87954
    NCBI Gene: 109861
  • Alliance
    gene page
Location &
Maps
more
  • Sequence Map
    Genome coordinates not available from the current reference assembly.
  • Genetic Map
    Chromosome 9, Syntenic
  • Mapping Data
    2 experiments
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotypes from 1 allele in 2 genetic backgrounds
    2 images
    2 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Heterozygotes show low penetrance of the phenotype which includes syndactyly of the hindfeet and a kinky tail.
Sequences &
Gene Models
less
Other
Accession IDs
less
MGD-MRK-1178
References
more
  • Summaries
    All 3
    Phenotypes 2
  • Earliest
    J:81166 Ruvinsky I, et al., Genetics analysis of mouse mutations Abnormal feet and tail and rough coat, which cause developmental abnormalities and alopecia. Mamm Genome. 2002 Dec;13(12):675-9
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory