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Gene Expression Data
Assay Details
Assay
Reference: J:361577 Hu B, et al., Increased cardiac macrophages in Sorbs2-deficient hearts: revealing a potential role for macrophage in responding to embryonic myocardial abnormalities. Front Genet. 2024;15:1525931
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7861867
Gene symbol: Adgre1
Gene name: adhesion G protein-coupled receptor E1
Antibody: anti-F4/80
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
Results
Specimen 2A WT Ventral: embryonic day 12.5 (more )
Structure Cell Type Level Pattern Image Note
TS20: heart left ventricle macrophage Present 2A WT Ventral
TS20: heart right ventricle macrophage Present 2A WT Ventral
Specimen 2A WT Dorsal: embryonic day 12.5 (more )
Structure Cell Type Level Pattern Image Note
TS20: heart left ventricle macrophage Present 2A WT Dorsal
TS20: heart right ventricle macrophage Present 2A WT Dorsal
Specimen 2A WT Lateral: embryonic day 12.5 (more )
Structure Cell Type Level Pattern Image Note
TS20: heart left ventricle macrophage Present 2A WT Lateral
Specimen 2A Sorbs2-/- Ventral: embryonic day 12.5; Sorbs2tm1.2Gfng/Sorbs2tm1.2Gfng (more )
Structure Cell Type Level Pattern Image Note
TS20: heart left ventricle macrophage Present 2A Sorbs2-/- Ventral
TS20: heart right ventricle macrophage Present 2A Sorbs2-/- Ventral
Specimen 2A Sorbs2-/- Dorsal: embryonic day 12.5; Sorbs2tm1.2Gfng/Sorbs2tm1.2Gfng (more )
Structure Cell Type Level Pattern Image Note
TS20: heart left ventricle macrophage Present 2A Sorbs2-/- Dorsal
TS20: heart right ventricle macrophage Present 2A Sorbs2-/- Dorsal
Specimen 2A Sorbs2-/- Lateral: embryonic day 12.5; Sorbs2tm1.2Gfng/Sorbs2tm1.2Gfng (more )
Structure Cell Type Level Pattern Image Note
TS20: heart left ventricle macrophage Present 2A Sorbs2-/- Lateral
Specimen 2B WT: embryonic day 12.5 (more )
Structure Cell Type Level Pattern Image Note
TS20: visceral pericardium macrophage Present Regionally restricted 2B WT Expression in macrophages mainly distributed under epicardium.
TS20: cardiac muscle tissue Present Regionally restricted 2B WT Expression in outer layer of myocardium.
Specimen 2B Sorbs2-/-: embryonic day 12.5; Sorbs2tm1.2Gfng/Sorbs2tm1.2Gfng (more )
Structure Cell Type Level Pattern Image Note
TS20: heart macrophage Present 2B Sorbs2-/- Authors report increased macrophage counts.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory