Aim2 RNA in situ Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:359864 Chen Y, et al., The Ednrb-Aim2-AKT axis regulates neural crest-derived melanoblast proliferation during early development. Development. 2024 Nov 15;151(22):dev202444
Assay type:	RNA in situ
MGI Accession ID:	MGI:7861723
Gene symbol:	Aim2
Gene name:	absent in melanoma 2

Probe:	Aim2 probe
Probe preparation:	Antisense labelled with digoxigenin RNA
Visualized with:	Alkaline phosphatase

Results

3F WT left ©

3F WT right ©

Specimen 3F WT: embryonic day 12.5 (more

)

Structure	Level	Pattern	Image	Note
TS20: embryo	Present		3F WT left , 3F WT right

Specimen 3F Ednrb-/-: embryonic day 12.5; Ednrb^tm1Myks/Ednrb^tm1Myks (more

)

Structure	Level	Pattern	Image	Note
TS20: embryo	Strong		3F Ednrb-/- left , 3F Ednrb-/- right	Expression increased compared to wild type.

Specimen 3F Ednrb-/-;Aim2-/-: embryonic day 12.5; Aim2^em2.1Gpt/Aim2^em2.1Gpt, Ednrb^tm1Myks/Ednrb^tm1Myks (more

)

Structure	Level	Pattern	Image	Note
TS20: embryo	Absent		3F Ednrb-/-:Aim2-/- right , 3F Ednrb-/-:Aim2-/- left	Expression completely absent.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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