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Gene Expression Data
Assay Details
Assay
Reference: J:46754 Mitsiadis TA, et al., Expression of the transcription factors Otlx2, Barx1 and Sox9 during mouse odontogenesis. Eur J Oral Sci. 1998 Jan;106 Suppl 1:112-6
Assay type: RNA in situ
MGI Accession ID: MGI:7859728
Gene symbol: Pitx2
Gene name: paired-like homeodomain transcription factor 2
Probe: clone A7
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 1A: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: stomatodeum Strong Regionally restricted 1A Expression is in the ectoderm.
TS17: 1st branchial arch mandibular component ectoderm Strong Regionally restricted 1A Absent in the outer parts.
TS17: 1st branchial arch maxillary component ectoderm Strong Regionally restricted 1A Absent in the outer parts.
TS17: fronto-nasal process ectoderm Strong Regionally restricted 1A Absent in the outer parts.

Specimen 1C: embryonic day 18.5 (more )
Structure Cell Type Level Pattern Image Note
TS26: outer enamel epithelium Strong 1C
TS26: stratum intermedium Strong 1C
TS26: 1st molar Present 1C
TS26: molar dental lamina Present 1C
TS26: 2nd molar Present 1C Expression is in the molar epithelium of the second molar.
TS26: molar epithelium Present 1C Expression is in the molar epithelium of the second molar.
TS26: incisor epithelium Present Regionally restricted 1C Expression is in the lingual and labial sides.
TS26: enamel organ preameloblast Weak Regionally restricted 1C Expression is downregulated in preameloblasts.
TS26: stellate reticulum Weak Regionally restricted 1C
TS26: incisor dental papilla Absent 1C
TS26: molar dental papilla Absent 1C

Specimen not shown E9.5: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: stomatodeum ectoderm Strong
TS15: 1st branchial arch mandibular component ectoderm Strong Regionally restricted Absent in the outer parts.
TS15: 1st branchial arch maxillary component ectoderm Strong Regionally restricted Absent in the outer parts.
TS15: fronto-nasal process ectoderm Strong Regionally restricted Absent in the outer parts.

Specimen not shown E13.5: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: 1st molar Strong
TS21: incisor Strong
TS21: oral epithelium Absent

Specimen not shown E16.5: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: 1st molar Strong
TS24: inner enamel epithelium Strong
TS24: outer enamel epithelium Strong
TS24: stratum intermedium Strong
TS24: incisor epithelium Present Regionally restricted Expression is in the epithelial derivatives, except for the inner enamel epithelium, both in the labial and in the lingual side.
TS24: stellate reticulum Weak


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory