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Gene Expression Data
Assay Details
Assay
Reference: J:294282 Li L, et al., The COMPASS Family Protein ASH2L Mediates Corticogenesis via Transcriptional Regulation of Wnt Signaling. Cell Rep. 2019 Jul 16;28(3):698-711.e5
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7855680
Gene symbol: Pou3f2
Gene name: POU domain, class 3, transcription factor 2
Results
Specimen 1E Brn2 Control: postnatal day 3; Tg(Dach1-cre)1Krs/0 (more )
Structure Cell Type Level Pattern Image Note
TS27: neocortex pyramidal neuron Present Regionally restricted 1E Brn2 Control Expression in upper layer projection neurons.
Specimen 1E Brn2 cKO: postnatal day 3; Ash2ltm1.1Bcgen/Ash2ltm1.1Bcgen, Tg(Dach1-cre)1Krs/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS27: neocortex Weak Regionally restricted 1E Brn2 cKO Signficant reduction in number of expressing cells compared to control.
Specimen S1H Brn2 Control: postnatal day 7; Tg(Dach1-cre)1Krs/0 (more )
Structure Cell Type Level Pattern Image Note
TS28: neocortex pyramidal neuron Present Regionally restricted S1H Brn2 Control Expression in upper layer projection neurons.
Specimen S1H Brn2 cKO: postnatal day 7; Ash2ltm1.1Bcgen/Ash2ltm1.1Bcgen, Tg(Dach1-cre)1Krs/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS27: neocortex Weak Regionally restricted S1H Brn2 cKO Authors report decreased upper layer marker expression.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory