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Gene Expression Data
Assay Details
Assay
Reference: J:153683 Jia L, et al., Retinoid-related orphan nuclear receptor RORbeta is an early-acting factor in rod photoreceptor development. Proc Natl Acad Sci U S A. 2009 Oct 13;106(41):17534-9
Assay type: RNA in situ
MGI Accession ID: MGI:7782370
Gene symbol: Crx
Gene name: cone-rod homeobox
Probe: mCrx probe
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 2B Crx +/+: postnatal day 6 (more )
Structure Level Pattern Image Note
TS28: retina outer nuclear layer Strong 2B Crx +/+ Peak expression at P6.
Specimen 2B Crx -/-: postnatal day 6; Rorbtm1Mba/Rorbtm1Mba (more )
Structure Level Pattern Image Note
TS28: retina outer nuclear layer Present 2B Crx -/- Authors report retention of expression.
Specimen S1A P6 +/+: postnatal day 6 (more )
Structure Level Pattern Image Note
TS28: retina outer nuclear layer Strong S1A P6 +/+
Specimen S1A P6 -/-: postnatal day 6; Rorbtm1Mba/Rorbtm1Mba (more )
Structure Level Pattern Image Note
TS28: retina outer nuclear layer Present Regionally restricted S1A P6 -/- Expression reduced, with relatively more dispersed pattern of expression compared to wild type.
Specimen S1A P14 +/+: postnatal day 14 (more )
Structure Level Pattern Image Note
TS28: retina outer nuclear layer Present S1A P14 +/+
Specimen S1A P14 -/-: postnatal day 14; Rorbtm1Mba/Rorbtm1Mba (more )
Structure Level Pattern Image Note
TS28: retina outer nuclear layer Present Regionally restricted S1A P14 -/- Expression reduced, with relatively more dispersed pattern of expression compared to wild type.
Specimen S1A P31 +/+: postnatal day 31 (more )
Structure Level Pattern Image Note
TS28: retina outer nuclear layer Present S1A P31 +/+
Specimen S1A P31 -/-: postnatal day 31; Rorbtm1Mba/Rorbtm1Mba (more )
Structure Level Pattern Image Note
TS28: retina outer nuclear layer Present Regionally restricted S1A P31 -/- Expression reduced, with relatively more dispersed pattern of expression compared to wild type.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory