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Gene Expression Data
Assay Details
Assay
Reference: J:347982 Li C, et al., Nesprin-2 is a novel scaffold protein for telethonin and FHL-2 in the cardiomyocyte sarcomere. J Biol Chem. 2024 Apr 2;300(5):107254
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7766928
Gene symbol: Syne2
Gene name: spectrin repeat containing, nuclear envelope 2
Results
Specimen 1B E12.5: embryonic day 12.5 (more )
Note: Double labeled: green - Syne2; red - Emd (assay MGI:7766929).
Structure Level Pattern Image Note
TS20: striated muscle tissue Present 1B E12.5 Expression is at the nuclear envelope and nuclear periphery.
Specimen 1B E16.5: embryonic day 16.5 (more )
Note: Double labeled: green - Syne2; magenta - alpha-actinin.
Structure Level Pattern Image Note
TS24: striated muscle tissue Present 1B E16.5 Expression is in the sarcomere.
Specimen 1B P2: postnatal day 2 (more )
Note: Double labeled: green - Syne2; magenta - alpha-actinin.
Structure Level Pattern Image Note
TS27: striated muscle tissue Present 1B P2 Expression is in the sarcomere.
Specimen 1B P14: postnatal day 14 (more )
Note: Double labeled: green - Syne2; magenta - alpha-actinin.
Structure Level Pattern Image Note
TS28: striated muscle tissue Present 1B P14 Expression is in the sarcomere.
Specimen 1C alpha-actinin: postnatal adult (more )
Note: Double labeled: green - Syne2; red - alpha-actinin.
Structure Level Pattern Image Note
TS28: cardiac muscle tissue Present 1C alpha-actinin Expression localized to the Z disc and I band and to the sarcoplasmic reticulum.
Specimen 1C Myomesin: postnatal adult (more )
Note: Double labeled: green - Syne2; red - Myom1 (assay MGI:7766930).
Structure Level Pattern Image Note
TS28: cardiac muscle tissue Present 1C Myomesin Expression localized to the Z disc and I band and to the sarcoplasmic reticulum.
Specimen 1C SERCA-2: postnatal adult (more )
Note: Double labeled: green - Syne2; red - Atp2a2 (assay MGI:7766931).
Structure Level Pattern Image Note
TS28: cardiac muscle tissue Present 1C SERCA-2 Expression localized to the Z disc and I band and to the sarcoplasmic reticulum.
Specimen 2C: postnatal adult (more )
Note: Double labeled: green - Syne2; red - Tcap (assay MGI:7766935).
Structure Level Pattern Image Note
TS28: cardiac muscle tissue Present 2C heart Nesprin-2 , 2C heart Merge Expression is at the to the Z-disc and I band of the sarcomere.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory