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Gene Expression Data
Assay Details
Assay
Reference: J:70388 Weinstein M, et al., Smad proteins and hepatocyte growth factor control parallel regulatory pathways that converge on beta1-integrin to promote normal liver development. Mol Cell Biol. 2001 Aug;21(15):5122-31
Assay type: Western blot
MGI Accession ID: MGI:7748805
Gene symbol: Smad2
Gene name: SMAD family member 2
Antibody: anti-Smad2
Detection system: Secondary antibody coupled to horseradish peroxidase
Results Image: 3A Smad2
 Sample Information Bands Other Sample Information
Lane AgeStructure Size Not Specified Genetic BackgroundMutant Allele(s)Sex
sm2/3 E14.5 TS22: liver Weak (a) involves: 129S6/SvEvTac * NIH Black Swiss Smad2tm1Cxd/Smad2+, Smad3tm1Cxd/Smad3+Not Specified
wt E14.5 TS22: liver Present involves: 129S6/SvEvTac * NIH Black Swiss Not Specified
Sm3+/- E14.5 TS22: liver Trace (b) involves: 129S6/SvEvTac * NIH Black Swiss Smad3tm1Cxd/Smad3+Not Specified
Sm3-/- E14.5 TS22: liver Strong (c) involves: 129S6/SvEvTac * NIH Black Swiss Smad3tm1Cxd/Smad3tm1CxdNot Specified
Notes:
(a) Expression decreased relative to wild type livers.
(b) Expression not increased in Smad3+/- livers.
(c) Expression level increased dramatically in Smad3-/- livers
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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