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Gene Expression Data
Assay Details
Assay
Reference: J:279388 Weiss AC, et al., Delayed onset of smooth muscle cell differentiation leads to hydroureter formation in mice with conditional loss of the zinc finger transcription factor gene Gata2 in the ureteric mesenchyme. J Pathol. 2019 Aug;248(4):452-463
Assay type: RNA in situ
MGI Accession ID: MGI:7718848
Gene symbol: Tagln
Gene name: transgelin
Probe: Tagln probe
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 2O: embryonic day 18.5; Gata2tm1Sac/? (more )
Note: Littermates without the Tbx18cre were used as control.
Structure Cell Type Level Pattern Image Note
TS26: ureteral smooth muscle layer ureter smooth muscle cell Present 2O
Specimen 2P: embryonic day 18.5; Gata2tm1Sac/Gata2tm1Sac, Tbx18tm4(cre)Akis/Tbx18+ (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS26: ureteral smooth muscle layer ureter smooth muscle cell Trace 2P Expression was severely reduced in the Gata2cKO.
Specimen 3C E14.5 control: embryonic day 14.5; Gata2tm1Sac/? (more )
Note: Littermates without the Tbx18cre were used as control.
Structure Level Pattern Image Note
TS22: ureteral mesenchyme Ambiguous 3C control E14.5 Tagln
Specimen 3C E14.5 Gata2cKO: embryonic day 14.5; Gata2tm1Sac/Gata2tm1Sac, Tbx18tm4(cre)Akis/Tbx18+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS22: ureteral mesenchyme Absent 3C Gata2cKO E14.5 Tagln
Specimen 3C E15.5 control: embryonic day 15.5; Gata2tm1Sac/? (more )
Note: Littermates without the Tbx18cre were used as control.
Structure Cell Type Level Pattern Image Note
TS23: ureteral smooth muscle layer ureter smooth muscle cell Present 3C control E15.5 Tagln
Specimen 3C E15.5 Gata2cKO: embryonic day 15.5; Gata2tm1Sac/Gata2tm1Sac, Tbx18tm4(cre)Akis/Tbx18+ (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS23: ureteral smooth muscle layer ureter smooth muscle cell Absent 3C Gata2cKO E15.5 Tagln
Specimen 3C E16.5 control: embryonic day 16.5; Gata2tm1Sac/? (more )
Note: Littermates without the Tbx18cre were used as control.
Structure Cell Type Level Pattern Image Note
TS24: ureteral smooth muscle layer ureter smooth muscle cell Present 3C control E16.5 Tagln
Specimen 3C E16.5 Gata2cKO: embryonic day 16.5; Gata2tm1Sac/Gata2tm1Sac, Tbx18tm4(cre)Akis/Tbx18+ (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS24: ureteral smooth muscle layer ureter smooth muscle cell Absent 3C Gata2cKO E16.5 Tagln
Specimen S4O: embryonic day 18.5; Gata2tm1Sac/? (more )
Note: Littermates without the Tbx18cre were used as control.
Structure Cell Type Level Pattern Image Note
TS26: ureteral smooth muscle layer ureter smooth muscle cell Present S4O in situ
Specimen S4P: embryonic day 18.5; Gata2tm1Sac/Gata2tm1Sac, Tbx18tm4(cre)Akis/Tbx18+ (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS26: ureteral smooth muscle layer ureter smooth muscle cell Trace S4P in situ Expression was severely reduced in the Gata2cKO.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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01/20/2026
MGI 6.24 		The Jackson Laboratory