About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:333283 Guan N, et al., Disruption of mitochondrial complex III in cap mesenchyme but not in ureteric progenitors results in defective nephrogenesis associated with amino acid deficiency. Kidney Int. 2022 Jul;102(1):108-120
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7718718
Gene symbol: Aqp2
Gene name: aquaporin 2
Results
Specimen 3c cortex Cre-: postnatal week 6; Uqcrqtm1.1Ncdl/Uqcrqtm1.1Ncdl (more )
Note: Double labeled: red - Aqp2; green - Atp6v1b1 (assay MGI:7718719).
Structure Level Pattern Image Note
TS28: cortical collecting duct Present 3c cortex left Coexpressed with Atp6v1b1.
Specimen 3c cortex Hoxb7-Qpc-/-: postnatal week 6; Tg(Hoxb7-cre)13Amc/0, Uqcrqtm1.1Ncdl/Uqcrqtm1.1Ncdl (more )
Note: Conditional mutant. Double labeled: red - Aqp2; green - Atp6v1b1 (assay MGI:7718719).
Structure Level Pattern Image Note
TS28: cortical collecting duct Present 3c cortex right Similar as in the control.
Specimen 3c medulla Cre-: postnatal week 6; Uqcrqtm1.1Ncdl/Uqcrqtm1.1Ncdl (more )
Note: Double labeled: red - Aqp2; green - Atp6v1b1 (assay MGI:7718719).
Structure Level Pattern Image Note
TS28: medullary collecting duct Present 3c medulla left Coexpressed with Atp6v1b1.
Specimen 3c medulla Hoxb7-Qpc-/-: postnatal week 6; Tg(Hoxb7-cre)13Amc/0, Uqcrqtm1.1Ncdl/Uqcrqtm1.1Ncdl (more )
Note: Conditional mutant. Double labeled: red - Aqp2; green - Atp6v1b1 (assay MGI:7718719).
Structure Level Pattern Image Note
TS28: medullary collecting duct Present 3c medulla right Similar as in the control.
Specimen 3d: postnatal week 6; Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo/Gt(ROSA)26Sor+, Tg(Hoxb7-cre)13Amc/0, Uqcrqtm1.1Ncdl/Uqcrqtm1.1Ncdl (more )
Note: Conditional mutant. Triple labeled: red - Aqp2; purple - Atp6v1b1 (assay MGI:7718720); green - Cre-recombination.
Structure Level Pattern Image Note
TS28: collecting duct Present 3d merge , 3d AQP2 Consistently coexpressed with eGFP, indicating that cells had undergone Cre-mediated recombination.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory