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Gene Expression Data
Assay Details
Assay
Reference: J:195264 Vincentz JW, et al., Twist1 Controls a Cell-Specification Switch Governing Cell Fate Decisions within the Cardiac Neural Crest. PLoS Genet. 2013 Mar;9(3):e1003405
Assay type: RNA in situ
MGI Accession ID: MGI:7643414
Gene symbol: Sox10
Gene name: SRY (sex determining region Y)-box 10
Probe: Sox10 probe
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 1E: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: outflow tract endocardial cushion Absent 1E Expression was not detected in the aorticopulmonary cushion tissue of the control.
Specimen 1F: embryonic day 11.5; H2az2Tg(Wnt1-cre)11Rth/0, Twist1tm1Bhr/Twist1tm2Bhr (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS19: outflow tract endocardial cushion Present Regionally restricted 1F Conditional ablation of Twist1 produces abnormal cellular aggregates. Expression of Sox10 was detected in the aggregates.
Specimen not shown: embryonic day 11.5; Twist1tm1Bhr/Twist1tm2Bhr, Hand1tm1.1(EGFP/cre)Abfi/Hand1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS19: outflow tract endocardial cushion Present Regionally restricted Conditional ablation of Twist1 produces abnormal cellular aggregates. Expression of Sox10 was detected in the aggregates.
Specimen 8G: embryonic day 12.5 (more )
Structure Cell Type Level Pattern Image Note
TS20: thoracic ganglion supporting cell Present 8G Sox10-expressing support cells surround the thoracic sympathetic chain ganglia.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory