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Gene Expression Data
Assay Details
Assay
Reference: J:340779 Di Bonito M, et al., Abnormal outer hair cell efferent innervation in Hoxb1-dependent sensorineural hearing loss. PLoS Genet. 2023 Sep;19(9):e1010933
Assay type: RNA in situ
MGI Accession ID: MGI:7628293
Gene symbol: Tbx20
Gene name: T-box 20
Probe: Tbx20 probe
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 4B Ctrl: postnatal day 8 (more )
Structure Level Pattern Image Note
TS28: trigeminal nucleus Present 4B Ctrl
TS28: brainstem nucleus Present Regionally restricted 4B Ctrl Expressed in the medial and lateral olivocochlear neurons.
Specimen 4B CKONkx2.2: postnatal day 8; Hoxb1tm1Mist/Hoxb1tm1Mist, Nkx2-2tm1.1(icre)Aholz/Nkx2-2+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: trigeminal nucleus Present 4B CKONkx2.2
TS28: brainstem nucleus Present Scattered 4B CKONkx2.2 Only few spread cells in the ventral olivocochlear region. Ectopic dispersed dorsally expressing cells are present in more dorsal locations.
Specimen 4B CKOr4: postnatal day 8; Hoxb1tm1Mist/Hoxb1tm1Mist, Tg(Hoxb1-cre)r4Mist/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: trigeminal nucleus Present 4B CKOr4
TS28: brainstem nucleus Present Scattered 4B CKOr4 Only few spread cells in the ventral olivocochlear region. Ectopic dispersed dorsally expressing cells are present in more dorsal locations.
Specimen 4B null: postnatal day 8; Hoxb1tm1.1Mist/Hoxb1tm1.1Mist (more )
Structure Level Pattern Image Note
TS28: trigeminal nucleus Present 4B null
TS28: brainstem nucleus Present Scattered 4B null No olivocochlear neurons were labeled. Ectopic dispersed dorsally expressing cells are present in more dorsal locations.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory