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Gene Expression Data
Assay Details
Assay
Reference: J:217209 Cottle DL, et al., Fetal inhibition of inflammation improves disease phenotypes in harlequin ichthyosis. Hum Mol Genet. 2015 Jan 15;24(2):436-49
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7621425
Gene symbol: Ccl11
Gene name: C-C motif chemokine ligand 11
Antibody: anti-CCL11 (bs1601R)
Detection system: Alexa Fluor
Results
Specimen 2J Wild type: embryonic day 18.5 (more )
Note: Double labeled: green - Ccl11; red - Krt14 (assay MGI:7621422).
Structure Level Pattern Image Note
TS26: epidermis granular layer Present 2J Wild type (merged) , 2J Wild type CCL11

Specimen 2J lx12/lx12: embryonic day 18.5; Abca12tm1Lex/Abca12tm1Lex (more )
Note: Double labeled: green - Ccl11; red - Krt14 (assay MGI:7621422).
Structure Level Pattern Image Note
TS26: epidermis granular layer Present Regionally restricted 2J lx12/lx12 (merged) , 2J lx12/lx12 CCL11 Expression expanded in granular layers of epidermis compared to wild type.

Specimen 3G Wild type E17.5: embryonic day 17.5 (more )
Note: Double labeled: green - Ccl11; red - Krt14 (assay MGI:7621422).
Structure Level Pattern Image Note
TS25: epidermis granular layer Present 3G E17.5 Wild type

Specimen 3G eI12/eI12 E17.5: embryonic day 17.5; Abca12el12/Abca12el12 (more )
Note: Double labeled: green - Ccl11; red - Krt14 (assay MGI:7621422).
Structure Level Pattern Image Note
TS25: epidermis granular layer Present 3G E17.5 eI12/eI12

Specimen 4F Wild type: embryonic day 18.5 (more )
Note: Double labeled: green - Ccl11; red - Krt14 (assay MGI:7621422).
Structure Level Pattern Image Note
TS26: epidermis granular layer Present 4F Wild type

Specimen 4F lx12/lx12: embryonic day 18.5; Abca12tm1Lex/Abca12tm1Lex (more )
Note: Double labeled: green - Ccl11; red - Krt14 (assay MGI:7621422).
Structure Level Pattern Image Note
TS26: epidermis granular layer Present 4F lx12/lx12


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/21/2024
MGI 6.23
The Jackson Laboratory