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Gene Expression Data
Assay Details
Assay
Reference: J:252079 McKee MD, et al., Compounded PHOSPHO1/ALPL deficiencies reduce dentin mineralization. J Dent Res. 2013 Aug;92(8):721-7
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7618591
Gene symbol: Phospho1
Gene name: phosphatase, orphan 1
Antibody: anti-PHOSPHO1
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
Results
Specimen 1A: embryonic day 18.0 (more )
Structure Level Pattern Image Note
TS26: lower jaw molar Absent 1A
Specimen 1A inset: embryonic day 18.0 (more )
Structure Cell Type Level Pattern Image Note
TS26: mandible alveolar process osteoblast Strong Regionally restricted 1A inset Strongly localizes to mandibular bone, especially on actively forming surfaces.
Specimen 1C: postnatal day 4 (more )
Structure Cell Type Level Pattern Image Note
TS28: dental alveolus osteoblast Present 1C
TS28: molar dental pulp odontoblast Present Regionally restricted 1C Strongest staining in newly differentiated odontoblasts as compared with the weaker staining of older odontoblasts found more occlusally.
TS28: enamel ameloblast Present Widespread 1C Expressed in ameloblasts throughout crown formation.
TS28: stratum intermedium Present 1C
Specimen 1E: postnatal day 4 (more )
Structure Cell Type Level Pattern Image Note
TS28: molar dental pulp odontoblast Present 1E
TS28: predentin Present 1E
TS28: stratum intermedium Present 1E
TS28: enamel ameloblast Present 1E
Specimen 1G: postnatal day 4 (more )
Structure Cell Type Level Pattern Image Note
TS28: dental alveolus osteoblast Present 1G
TS28: incisor dental pulp odontoblast Present 1G
Specimen S1 E18 molar: embryonic day 18.0 (more )
Structure Level Pattern Image Note
TS26: lower jaw molar Absent S1_E18 left
Specimen S1 E18 bone: embryonic day 18.0 (more )
Structure Cell Type Level Pattern Image Note
TS26: mandible osteoblast Strong Regionally restricted S1_E18 middle Strongly localizes to mandibular bone, especially on actively forming surfaces.
Specimen S1 P4 molar: postnatal day 4 (more )
Structure Cell Type Level Pattern Image Note
TS28: dental alveolus osteoblast Strong S1_P4 left , S1_P4 middle
TS28: molar dental pulp odontoblast Present S1_P4 left , S1_P4 middle
TS28: enamel ameloblast Present S1_P4 left , S1_P4 middle
Specimen S1 P4 incisor: postnatal day 4 (more )
Structure Cell Type Level Pattern Image Note
TS28: dental alveolus Strong S1_P4 right
TS28: incisor dental pulp odontoblast Present S1_P4 right
Specimen S1 P8 molar: postnatal day 8 (more )
Structure Cell Type Level Pattern Image Note
TS28: dental alveolus osteoblast Strong S1_P8 left , S1_P8 middle
TS28: molar dental pulp odontoblast Present S1_P8 left , S1_P8 middle
Specimen S1 P8 incisor: postnatal day 8 (more )
Structure Cell Type Level Pattern Image Note
TS28: dental alveolus osteoblast Strong S1_P8 right
TS28: incisor dental pulp odontoblast Present S1_P8 right
Specimen S1 P14 molar: postnatal day 14 (more )
Structure Cell Type Level Pattern Image Note
TS28: dental alveolus osteoblast Strong S1_P14 right , S1_P14 left
TS28: molar dental pulp odontoblast Present S1_P14 right , S1_P14 left
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory