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Gene Expression Data
Assay Details
Assay
Reference: J:83752 Cox PR, et al., Mice lacking Tropomodulin-2 show enhanced long-term potentiation, hyperactivity, and deficits in learning and memory. Mol Cell Neurosci. 2003 May;23(1):1-12
Assay type: Western blot
MGI Accession ID: MGI:7618457
Gene symbol: Tmod1
Gene name: tropomodulin 1
Antibody: anti-Tmod1
Detection system: Secondary antibody coupled to horseradish peroxidase
Assay notes: This assay was using B3 line (Tmod2<tm2Hzo>). Similar results were shown with the A12 line (Tmod2<tm1Hzo>).
Results Image: 6A Tmod1
 Sample Information Bands Other Sample Information
Lane AgeStructure 36 kDa (a) Genetic BackgroundMutant Allele(s)Sex
-/- P TS28: brain Strong (b) involves: 129S7/SvEvBrd * C57BL/6J Tmod2tm2Hzo/Tmod2tm2HzoNot Specified
+/- P TS28: brain Present (c) involves: 129S7/SvEvBrd * C57BL/6J Tmod2tm2Hzo/Tmod2+Not Specified
+/+ P TS28: brain Present involves: 129S7/SvEvBrd * C57BL/6J Not Specified
-/- P TS28: brain Strong (b) involves: 129S7/SvEvBrd * C57BL/6J Tmod2tm2Hzo/Tmod2tm2HzoNot Specified
+/- P TS28: brain Present (c) involves: 129S7/SvEvBrd * C57BL/6J Tmod2tm2Hzo/Tmod2+Not Specified
+/+ P TS28: brain Present involves: 129S7/SvEvBrd * C57BL/6J Not Specified
-/- P TS28: brain Strong (b) involves: 129S7/SvEvBrd * C57BL/6J Tmod2tm2Hzo/Tmod2tm2HzoNot Specified
+/- P TS28: brain Present (c) involves: 129S7/SvEvBrd * C57BL/6J Tmod2tm2Hzo/Tmod2+Not Specified
+/+ P TS28: brain Present involves: 129S7/SvEvBrd * C57BL/6J Not Specified
Notes:
(a) Data was quantified in upper graph.
(b) Expression increased about eightfold compared with the wild-type.
(c) Expression increased about twofold compared with the wild-type.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory