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Gene Expression Data
Assay Details
Assay
Reference: J:74283 Chan R, et al., The Catalytic Activity of the ErbB-2 Receptor Tyrosine Kinase Is Essential for Embryonic Development. Mol Cell Biol. 2002 Feb;22(4):1073-8
Assay type: Western blot
MGI Accession ID: MGI:7616841
Gene symbol: Erbb2
Gene name: erb-b2 receptor tyrosine kinase 2
Antibody: anti-c-ErbB2/c-Neu (ab-3)
Detection system: horseradish peroxidase
Results Image: 5A ErbB-2
 Sample Information Bands Other Sample Information
Lane AgeStructure Size Not Specified Genetic BackgroundMutant Allele(s)Sex
wt/wt E10.5 TS17: embryo Present Not Specified Not Specified
wt/wt E10.5 TS17: embryo Present Not Specified Not Specified
KI/KI E10.5 TS17: embryo Weak (a) involves: 129S1/Sv * 129X1/SvJ * BALB/c Erbb2tm2Mul/Erbb2tm2MulNot Specified
KI/KI E10.5 TS17: embryo Weak (a) involves: 129S1/Sv * 129X1/SvJ * BALB/c Erbb2tm2Mul/Erbb2tm2MulNot Specified
KD/KD E10.5 TS17: embryo Weak (a) involves: 129S1/Sv * 129X1/SvJ * BALB/c Erbb2tm1Mul/Erbb2tm1MulNot Specified
KD/KD E10.5 TS17: embryo Weak (a) involves: 129S1/Sv * 129X1/SvJ * BALB/c Erbb2tm1Mul/Erbb2tm1MulNot Specified
wt/KD E10.5 TS17: embryo Present involves: 129S1/Sv * 129X1/SvJ * BALB/c Erbb2tm1Mul/Erbb2+Not Specified
wt/KI E10.5 TS17: embryo Present involves: 129S1/Sv * 129X1/SvJ * BALB/c Erbb2tm2Mul/Erbb2+Not Specified
Notes:
(a) Expression level only 10-15% compared to wild type embryos. Authors report similar levels of expression between mutants.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/14/2024
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