Gene Expression Data
Assay Details
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Assay
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Reference:
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J:293098
Jafree DJ, et al., Spatiotemporal dynamics and heterogeneity of renal lymphatics in mammalian development and cystic kidney disease. Elife. 2019 Dec 6;8:e48183
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Assay type:
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In situ reporter (knock in)
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MGI Accession ID:
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MGI:7614842
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Gene symbol:
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Vegfc
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Gene name:
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vascular endothelial growth factor C
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Reporter:
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lacZ
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Direct Detection
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Results
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Specimen
1-S4A:
embryonic day 15.5; Vegfctm1Ali/Vegfc +
(more  )
Specimen
1-S4A:
(close  )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ * CD-1
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Mutant Allele(s):
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Vegfctm1Ali/Vegfc+
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Age:
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embryonic day 15.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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2% Paraformaldehyde
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| Structure |
Level |
Pattern |
Image |
Note |
| TS23: metanephros |
Present |
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1-S4A right
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Expressed in a branching pattern, mimicking the appearance of the renal arterial tree.
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Specimen
1-S4B left:
embryonic day 16.5; Vegfctm1Ali/Vegfc +
(more )
Note: Double labeled: blue - Vegfc reporter; brown - Lyve1 (assay MGI:7615025).
Specimen
1-S4B left:
(close )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ * CD-1
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Mutant Allele(s):
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Vegfctm1Ali/Vegfc+
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Age:
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embryonic day 16.5
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Sex:
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Not Specified
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Type:
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section from whole mount
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Fixation:
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2% Paraformaldehyde
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Embedding:
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Paraffin
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Note:
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Double labeled: blue - Vegfc reporter; brown - Lyve1 (assay MGI:7615025).
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Specimen
1-S4B right:
embryonic day 16.5; Vegfctm1Ali/Vegfc +
(more )
Specimen
1-S4B right:
(close )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ * CD-1
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Mutant Allele(s):
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Vegfctm1Ali/Vegfc+
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Age:
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embryonic day 16.5
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Sex:
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Not Specified
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Type:
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section from whole mount
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Fixation:
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2% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
| TS24: renal interstitium |
kidney interstitial cell |
Strong |
Regionally restricted |
1-S4B right
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Expressed in interstitial cells beneath the pelvis and adjacent arterioles.
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Analysis Tools