Prrt2 Immunohistochemistry Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:299667 Calame DJ, et al., Presynaptic PRRT2 Deficiency Causes Cerebellar Dysfunction and Paroxysmal Kinesigenic Dyskinesia. Neuroscience. 2020 Nov 10;448:272-286
Assay type:	Immunohistochemistry
MGI Accession ID:	MGI:7610590
Gene symbol:	Prrt2
Gene name:	proline-rich transmembrane protein 2

Antibody:	Anti-PRRT2 (HPA014447)
Detection system:	Secondary antibody coupled to Alexa Fluor

Results

4C +/+ merge ©

4C +/+ PRRT2 ©

Specimen 4C +/+: postnatal (more

)
Note: Double labeled: blue - Prrt2; green - Gria1 (assay MGI:7610591).

Structure	Level	Pattern	Image	Note
TS28: cerebellum granule cell layer	Present		4C +/+ merge , 4C +/+ PRRT2	Minimal colocalization with GluR1/Gria1.
TS28: cerebellum molecular layer	Present		4C +/+ merge , 4C +/+ PRRT2	Minimal colocalization with GluR1/Gria1.

4C -/- merge ©

4C -/- PRRT2 ©

Specimen 4C -/-: postnatal; Prrt2^{tm1d(KOMP)Wtsi}/Prrt2^{tm1d(KOMP)Wtsi} (more

)
Note: Double labeled: blue - Prrt2; green - Gria1 (assay MGI:7610591).

Structure	Level	Pattern	Image	Note
TS28: cerebellum granule cell layer	Absent		4C -/- PRRT2 , 4C -/- merge
TS28: cerebellum molecular layer	Absent		4C -/- PRRT2 , 4C -/- merge

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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