Zc4h2 Immunohistochemistry Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:286599 Song NN, et al., Rnf220/Zc4h2-mediated monoubiquitylation of Phox2 is required for noradrenergic neuron development. Development. 2020 Mar 30;147(6):dev185199
Assay type:	Immunohistochemistry
MGI Accession ID:	MGI:7608331
Gene symbol:	Zc4h2
Gene name:	zinc finger, C4H2 domain containing

Antibody:	anti-Zc4h2
Detection system:	Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase

Results

1A Zc4h2 ©

Specimen 1A Zc4h2: embryonic day 10.5 (more

)

Structure	Level	Pattern	Image	Note
TS17: rhombomere 1	Absent		1A Zc4h2	No expression in dorsal rhombomere 1.

1B Dbh/Zc4h2 ©

Specimen 1B Dbh/Zc4h2: embryonic day 12.5 (more

)
Note: Double labeled: brown - Zc4h2; blue - Dbh (assay MGI:7608298).

Structure	Cell Type	Level	Pattern	Image	Note
TS20: pons	noradrenergic neuron	Present	Regionally restricted	1B Dbh/Zc4h2	Expression in Dbh-expressing noradrenergic neurons. Also expressed in cells located located ventrolateral to noradrenergic neurons.

S1D ©

Specimen S1D Rnf220/Zc4h2: embryonic day 11.5 (more

)
Note: Double labeled: brown - Zc4h2; blue - Rnf220 (assay MGI:7608312).

Structure	Cell Type	Level	Pattern	Image	Note
TS19: metencephalon basal plate mantle layer	noradrenergic neuron	Present	Regionally restricted	S1D	Expression colocalized with Rnf220 expression in locus coeruleus noradrenergic neurons.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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