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Gene Expression Data
Assay Details
Assay
Reference: J:304350 Carley E, et al., The LINC complex transmits integrin-dependent tension to the nuclear lamina and represses epidermal differentiation. Elife. 2021 Mar;:e58541
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7580406
Gene symbol: Ivl
Gene name: involucrin
Antibody: anti-Involucrin
Detection system: Secondary antibody coupled to Alexa Fluor
Results
Specimen S3 Figure 2C WT: embryonic day 15.5 (more )
Structure Cell Type Level Pattern Image Note
TS23: epidermis spinous layer keratinocyte Present S3 Figure 2C WT Expression is in spinous keratinocytes.
TS23: epidermis keratinocyte Present Regionally restricted S3 Figure 2C WT Expression is in granular keratinocytes.
Specimen S3 Figure 2C dKO: embryonic day 15.5; Sun1tm1Mhan/Sun1tm1Mhan, Sun2tm1Mhan/Sun2tm1Mhan (more )
Structure Cell Type Level Pattern Image Note
TS23: epidermis spinous layer keratinocyte Present S3 Figure 2C Sun dKO The expressing layer has expanded in this mutant compared to wild-type.
TS23: epidermis keratinocyte Present Regionally restricted S3 Figure 2C Sun dKO The expressing granular layer has expanded in this mutant compared to wild-type.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/16/2024
MGI 6.23 		The Jackson Laboratory