Pmvk RNA in situ Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:316178 Gamart J, et al., SMAD4 target genes are part of a transcriptional network that integrates the response to BMP and SHH signaling during early limb bud patterning. Development. 2021 Dec 1;148(23):dev200182
Assay type:	RNA in situ
MGI Accession ID:	MGI:7576869
Gene symbol:	Pmvk
Gene name:	phosphomevalonate kinase

Probe:	Pmvk probe
Probe preparation:	Antisense labelled with digoxigenin RNA
Visualized with:	Alkaline phosphatase

Results

S2_Pmvk WT ©

Specimen S2 Pmvk WT: embryonic day 10.0; Tg(Prrx1-cre)1Cjt/0 (more

)

Structure	Level	Pattern	Image	Note
TS16: forelimb bud	Present	Uniform	S2_Pmvk WT

Specimen S2 Pmvk delta/deltac: embryonic day 10.0; Smad4^tm2.1Cxd/Smad4^tm2.2Cxd, Tg(Prrx1-cre)1Cjt/0 (more

)
Note: Conditional mutant.

Structure	Level	Pattern	Image	Note
TS16: forelimb bud	Weak		S2_Pmvk delta/deltac	Expression reduced compared to control.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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