Id1 RNA in situ Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:316178 Gamart J, et al., SMAD4 target genes are part of a transcriptional network that integrates the response to BMP and SHH signaling during early limb bud patterning. Development. 2021 Dec 1;148(23):dev200182
Assay type:	RNA in situ
MGI Accession ID:	MGI:7576853
Gene symbol:	Id1
Gene name:	inhibitor of DNA binding 1, HLH protein

Probe:	Id1 probe
Probe preparation:	Antisense labelled with digoxigenin RNA
Visualized with:	Alkaline phosphatase

Results

6B Id1 WT ©

Specimen 6B Id1 WT: embryonic day 10.0; Tg(Prrx1-cre)1Cjt/0 (more

)

Structure	Level	Pattern	Image	Note
TS16: forelimb bud	Present		6B Id1 WT

Specimen 6B Id1 delta/deltac: embryonic day 10.0; Smad4^tm2.1Cxd/Smad4^tm2.2Cxd, Tg(Prrx1-cre)1Cjt/0 (more

)
Note: Conditional mutant.

Structure	Level	Pattern	Image	Note
TS16: forelimb bud mesenchyme	Present	Regionally restricted	6B Id1 delta/deltac	Authors report spatial alterations of expression in anterior mesenchyme.

S5B Id1 WT ©

Specimen S5B Id1 E10.5 WT: embryonic day 10.5; Tg(Prrx1-cre)1Cjt/0 (more

)

Structure	Level	Pattern	Image	Note
TS17: forelimb bud	Present		S5B Id1 WT

Specimen S5B Id1 E10.5 delta/deltac: embryonic day 10.5; Smad4^tm2.1Cxd/Smad4^tm2.2Cxd, Tg(Prrx1-cre)1Cjt/0 (more

)
Note: Conditional mutant.

Structure	Level	Pattern	Image	Note
TS17: forelimb bud	Present	Regionally restricted	S5B Id1 delta/deltac	Authors report differential expression compared to control.

S6_Id1 WT ©

Specimen S6 Id1 E10.75 WT: embryonic day 10.75 (more

)

Structure	Level	Pattern	Image	Note
TS18: forelimb bud	Present		S6_Id1 WT

Specimen S6 Id1 E10.75 Shh delta/delta: embryonic day 10.75; Shh^{tm1(EGFP/cre)Cjt}/Shh^{tm1(EGFP/cre)Cjt} (more

)

Structure	Level	Pattern	Image	Note
TS18: forelimb bud	Present		S6_Id1 delta/deltac

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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