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Gene Expression Data
Assay Details
Assay
Reference: J:316178 Gamart J, et al., SMAD4 target genes are part of a transcriptional network that integrates the response to BMP and SHH signaling during early limb bud patterning. Development. 2021 Dec 1;148(23):dev200182
Assay type: RNA in situ
MGI Accession ID: MGI:7576849
Gene symbol: Mvk
Gene name: mevalonate kinase
Probe: Mvk probe
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 4C Mvk WT: embryonic day 10.0; Tg(Prrx1-cre)1Cjt/0 (more )
Structure Level Pattern Image Note
TS16: forelimb bud Present 4C Mvk WT
Specimen 4C Mvk delta/deltac: embryonic day 10.0; Smad4tm2.1Cxd/Smad4tm2.2Cxd, Tg(Prrx1-cre)1Cjt/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS16: forelimb bud Present Regionally restricted 4C Mvk delta/deltac Expression clearly altered compared to control.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory