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Gene Expression Data
Assay Details
Assay
Reference: J:338194 Sulic AM, et al., Transcriptomic landscape of early hair follicle and epidermal development. Cell Rep. 2023 Jun 13;42(6):112643
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:7574113
Gene symbol: Cyfip2
Gene name: cytoplasmic FMR1 interacting protein 2
Reporter: lacZ
Antibody: anti-B-galactosidase
Detection system: Secondary antibody coupled to Alexa Fluor
Results
Specimen 1F Cyfip2-lacZ top: embryonic day 15.5; Cyfip2tm1a(EUCOMM)Wtsi/Cyfip2+, Shhtm1(EGFP/cre)Cjt/Shh+ (more )
Note: Conditional mutant. Triple labeled: magenta - Cyfip2 reporter; white - Epcam (assay MGI:7574119); green - Shh reporter (assay MGI:7574114).
Structure Level Pattern Image Note
TS23: back skin Present Regionally restricted 1F Cyfip2-LacZ top , 1F merged top Authors report colocalization with Shh expression.
Specimen 1F Cyfip2-lacZ bottom: embryonic day 15.5; Cyfip2tm1a(EUCOMM)Wtsi/Cyfip2+, Shhtm1(EGFP/cre)Cjt/Shh+ (more )
Note: Conditional mutant. Triple labeled: magenta - Cyfip2 reporter; white - Epcam (assay MGI:7574119); green - Shh reporter (assay MGI:7574114).
Structure Level Pattern Image Note
TS23: hair epidermal placode Present 1F Cyfip2-LacZ bottom , 1F merged bottom Authors report colocalization with Shh expression.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/30/2024
MGI 6.23 		The Jackson Laboratory