About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:305107 Ulisse V, et al., Regulation of axonal morphogenesis by the mitochondrial protein Efhd1. Life Sci Alliance. 2020 Jul;3(7)
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7567832
Gene symbol: Tubb3
Gene name: tubulin, beta 3 class III
Results
Specimen 1C: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: limb Present 1C
Specimen 1D: embryonic day 13.5; Stk11tm1.1Rdp/Stk11tm1.1Rdp, H2az2Tg(Wnt1-cre)11Rth/H2az2+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS21: limb Present 1D Reduced axonal morphogenesis compared to wild type.
Specimen S4D: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: limb Present S4D
Specimen S4E: embryonic day 13.5; Efhd1em1Wei/Efhd1em1Wei (more )
Structure Level Pattern Image Note
TS21: limb Present S4E Axonal pattern identical to wild type.
Specimen 2C: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: limb Present 2C
Specimen 2D: embryonic day 14.5; Efhd1em1Wei/Efhd1em1Wei (more )
Structure Level Pattern Image Note
TS22: limb Present Regionally restricted 2D Significant reduction in overall axonal coverage and decrease in total number of branches compared to wild type.
Specimen 2N: postnatal adult (more )
Structure Level Pattern Image Note
TS28: hindlimb skin Present 2N
Specimen 2O: postnatal adult; Efhd1em1Wei/Efhd1em1Wei (more )
Structure Level Pattern Image Note
TS28: hindlimb skin Present 2O Significant difference in number of terminal fibers in hinklimb skin compared with wild type.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory