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Gene Expression Data
Assay Details
Assay
Reference: J:343157 Snippert HJ, et al., Prominin-1/CD133 marks stem cells and early progenitors in mouse small intestine. Gastroenterology. 2009 Jun;136(7):2187-2194.e1
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7564467
Gene symbol: Prom1
Gene name: prominin 1
Antibody: CD133 (Prominin-1) Monoclonal Antibody (13A4)
Detection system: Secondary antibody coupled to Alexa Fluor 555
Results
Specimen 2C: postnatal adult (more )
Note: Wild type. Double labeled: blue - Prom1; purple - DAPI.
Structure Level Pattern Image Note
TS28: small intestine crypt of lieberkuhn Present Regionally restricted 2C Expression is seen in the bottom of the crypts.
Specimen 2D: postnatal adult; Lgr5tm1(cre/ERT2)Cle/Lgr5+ (more )
Note: Double labeled: blue - Prom1; green - Lgr5 reporter (assay MGI:7564464).
Structure Level Pattern Image Note
TS28: small intestine crypt of lieberkuhn Present Regionally restricted 2D Expression is seen in the bottom of the crypts; it is detected on the apical membranes of Lgr5+ intestinal stem cells and on transit-amplifying progenitors that are located above the Paneth cells.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/16/2024
MGI 6.23 		The Jackson Laboratory