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Gene Expression Data
Assay Details
Assay
Reference: J:330216 Li J, et al., The transcriptional coactivator Eya1 exerts transcriptional repressive activity by interacting with REST corepressors and REST-binding sequences to maintain nephron progenitor identity. Nucleic Acids Res. 2022 Oct 14;50(18):10343-10359
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7564133
Gene symbol: Six2
Gene name: sine oculis-related homeobox 2
Antibody: SIX2 monoclonal antibody (66347-1-Ig), clone 1F9G11
Detection system: Secondary antibody coupled to fluorescein
Results
Specimen 4F: embryonic day 17.5 (more )
Note: Double labeled: green - Six2; red - Rest (assay MGI:7564130).
Structure Level Pattern Image Note
TS25: cap mesenchyme Present 4F right Coexpressed with Rest in nephron progenitor cells in cap mesenchyme surrounding ureteric bud.
Specimen 5E: embryonic day 17.5 (more )
Note: Double labeled: green - Six2; red - Hltf (assay MGI:7564134).
Structure Level Pattern Image Note
TS25: cap mesenchyme Present 5E left , 5E right Coexpressed with Hltf in nephron progenitor cells in cap mesenchyme surrounding ureteric bud.
Specimen 7D: embryonic day 17.5 (more )
Note: Double labeled: green - Six2; red - Cdyl (assay MGI:7564135).
Structure Level Pattern Image Note
TS25: cap mesenchyme Present 7D lower Coexpressed with Cdyl in nephron progenitor cells in cap mesenchyme surrounding ureteric bud.
Specimen S4C left: embryonic day 17.5 (more )
Note: Double labeled: green - Six2; red - Rest (assay MGI:7564130).
Structure Level Pattern Image Note
TS25: cap mesenchyme Present S4C lower left Coexpressed with Rest in nephron progenitor cells in cap mesenchyme surrounding ureteric bud.
Specimen S4C right: embryonic day 17.5 (more )
Note: Double labeled: green - Six2; red - Rest (assay MGI:7564130).
Structure Level Pattern Image Note
TS25: cap mesenchyme Present S4C lower right Coexpressed with Rest in nephron progenitor cells in cap mesenchyme surrounding ureteric bud.
Specimen S5D: embryonic day 16.5 (more )
Note: Double labeled: green - Six2; red - Hltf (assay MGI:7564134).
Structure Level Pattern Image Note
TS24: cap mesenchyme Present S5D right , S5D left Coexpressed with Hltf in nephron progenitor cells in cap mesenchyme surrounding ureteric bud.
Specimen S7B: embryonic day 17.5 (more )
Note: Double labeled: green - Six2; red - Cdyl (assay MGI:7564135).
Structure Level Pattern Image Note
TS25: cap mesenchyme Present S7B right Coexpressed with Cdyl in nephron progenitor cells in cap mesenchyme surrounding ureteric bud.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/07/2024
MGI 6.23 		The Jackson Laboratory