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Gene Expression Data
Assay Details
Assay
Reference: J:217461 Yang G, et al., An eIF4E1/4E-T complex determines the genesis of neurons from precursors by translationally repressing a proneurogenic transcription program. Neuron. 2014 Nov 19;84(4):723-39
Assay type: RNA in situ
MGI Accession ID: MGI:7564091
Gene symbol: Neurog2
Gene name: neurogenin 2
Probe: Mm-Neurog2 (417291)
Probe preparation: Antisense DNA
Results
Specimen 7A neurogenin2: embryonic day 15.0 (more )
Structure Level Pattern Image Note
TS23: cerebral cortex subventricular zone Present 7A neurogenin2 Expression enriched in cells of ventricular zone/ subventricular zone.
TS23: cerebral cortex ventricular layer Present 7A neurogenin2 Expression enriched in cells of ventricular zone/ subventricular zone.

Specimen S5A neurogenin2: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: cerebral cortex subventricular zone Present S5A neurogenin2 anti-sense (lower) , S5A neurogenin2 anti-sense (upper)
TS20: cerebral cortex ventricular layer Present S5A neurogenin2 anti-sense (lower) , S5A neurogenin2 anti-sense (upper)

Specimen 7C neurogenin2: embryonic day 15.0 (more )
Note: Double labeled: red - Neurog2; green - Eif4enif1 (assay MGI:7564070).
Structure Level Pattern Image Note
TS23: cerebral cortex ventricular layer Present Regionally restricted 7C neurogenin2 YZ , 7C Merge XZ , 7C neurogenin2 , 7C Merge , 7C Merge YZ , 7C neurogenin2 XZ Expression partially colocalized with Eif4nif1 expressing foci.

Specimen 8A neurogenin2: embryonic day 12.0 (more )
Note: Double labeled: red - Neurog2; green - Eif4enif1 (assay MGI:7564070).
Structure Level Pattern Image Note
TS20: cerebral cortex subventricular zone Present Regionally restricted 8A (left) Expression predominantly in cycling precursors. Approximately 37.7% of foci colocalized with Eif4nif1 at this stage.
TS20: cerebral cortex ventricular layer Present Regionally restricted 8A (left) Expression predominantly in cycling precursors. Approximately 37.7% of foci colocalized with Eif4nif1 at this stage.

Specimen 8A neurogenin2 (top): embryonic day 12.0 (more )
Note: Double labeled: red - Neurog2; green - Eif4enif1 (assay MGI:7564070).
Structure Level Pattern Image Note
TS20: cerebral cortex subventricular zone Present Regionally restricted 8A (top right)

Specimen 8A neurogenin2 (middle): embryonic day 12.0 (more )
Note: Double labeled: red - Neurog2; green - Eif4enif1 (assay MGI:7564070).
Structure Level Pattern Image Note
TS20: cerebral cortex subventricular zone Present Regionally restricted 8A (middle) Highest proportion of expressing foci at interface of ventricular zone and subventricular zones (bin 2).
TS20: cerebral cortex ventricular layer Present Regionally restricted 8A (middle) Highest proportion of expressing foci at interface of ventricular zone and subventricular zones (bin 2).

Specimen 8A neurogenin2 (bottom): embryonic day 12.0 (more )
Note: Double labeled: red - Neurog2; green - Eif4enif1 (assay MGI:7564070).
Structure Level Pattern Image Note
TS20: cerebral cortex ventricular layer Present Regionally restricted 8A (bottom) Co-expression with Eif4nif1 most enriched in apical-most region (bin 1).

Specimen 8E neurogenin2 mRNA: embryonic day 12.0 (more )
Note: Triple labeled: red - Neurog2 RNA; green - Eif4enif1 (assay MGI:7564070); blue - Neurog2 protein (assay MGI:7564072).
Structure Level Pattern Image Note
TS20: cerebral cortex Present Regionally restricted 8E (left) Expression in all Neurog2 protein expressing cells, but also in cells not expressing Neurog2 protein.

Specimen 8E neurogenin2 mRNA (upper): embryonic day 12.0 (more )
Note: Triple labeled: red - Neurog2 RNA; green - Eif4enif1 (assay MGI:7564070); blue - Neurog2 protein (assay MGI:7564072).
Structure Level Pattern Image Note
TS20: cerebral cortex Present Regionally restricted 8E neurogenin2 mRNA (upper) , 8E Merge (upper) Expression in all Neurog2 protein expressing cells, but also in cells not expressing Neurog2 protein.

Specimen 8E neurogenin2 mRNA (lower): embryonic day 12.0 (more )
Note: Triple labeled: red - Neurog2 RNA; green - Eif4enif1 (assay MGI:7564070); blue - Neurog2 protein (assay MGI:7564072).
Structure Level Pattern Image Note
TS20: cerebral cortex Present Regionally restricted 8E neurogenin2 mRNA (lower) , 8E Merge (lower) Expression in all Neurog2 protein expressing cells, but also in cells not expressing Neurog2 protein.


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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory