About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:233705 Zhao H, et al., Deletions of Retinoblastoma 1 (Rb1) and Its Repressing Target S Phase Kinase-associated protein 2 (Skp2) Are Synthetic Lethal in Mouse Embryogenesis. J Biol Chem. 2016 May 6;291(19):10201-9
Assay type: RT-PCR
MGI Accession ID: MGI:7562464
Gene symbol: Trp73
Gene name: transformation related protein 73
Probe: p73 pF, p73 pR
Assay notes: Quantitative RT-PCR. Relative expression was normalized to Gapdh.
Results
Image: 5B p73 ©

 Sample Information Bands Other Sample Information
Lane AgeStructure Size Not Specified Amount Genetic BackgroundMutant Allele(s)Sex Note
Rb1lox/lox E13.5 TS21: brain Present 2.5 µg; total RNA involves: 129 * C57BL/6J * FVB Rb1tm3Tyj/Rb1tm3TyjNot Specified
Nes-Cre;Rb1lox/lox E13.5 TS21: brain Present (a) 2.5 µg; total RNA involves: 129 * C57BL/6J * FVB Rb1tm3Tyj/Rb1tm3Tyj, Tg(Nes-cre)1Kln/0Not Specified Conditional mutant.
Rb1lox/lox;Skp2-/- E13.5 TS21: brain Present (a) 2.5 µg; total RNA involves: 129 * C57BL/6J * FVB Rb1tm3Tyj/Rb1tm3Tyj, Skp2tm1Kin/Skp2tm1KinNot Specified
Nes-Cre;Rb1lox/lox;Skp2-/- E13.5 TS21: brain Present (b) 2.5 µg; total RNA involves: 129 * C57BL/6J * FVB Rb1tm3Tyj/Rb1tm3Tyj, Skp2tm1Kin/Skp2tm1Kin, Tg(Nes-cre)1Kln/0, Trp53tm1Brn/Trp53tm1BrnNot Specified Conditional mutant.
Notes:
(a) Similar as in the Rb1<lox/lox>.
(b) Increased expression compared with the control.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
05/14/2024
MGI 6.23
The Jackson Laboratory