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Gene Expression Data
Assay Details
Assay
Reference: J:273130 Ding W, et al., Cenpj Regulates Cilia Disassembly and Neurogenesis in the Developing Mouse Cortex. J Neurosci. 2019 Mar 13;39(11):1994-2010
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7547343
Gene symbol: Sox2
Gene name: SRY (sex determining region Y)-box 2
Antibody: Anti-Sox2 (Y-17; sc-17320)
Detection system: Secondary antibody coupled to Alexa Fluor
Results
Specimen 4F Sox2 Cenpj+/+: embryonic day 15.5 (more )
Note: Double labeled: red - Sox2; green - Eomes (assay MGI:7547344).
Structure Cell Type Level Pattern Image Note
TS23: cerebral cortex neural progenitor cell Present 4F Cenpj+/+ Merge (left) , 4F Cenpj+/+ Sox2
Specimen 4F Sox2 CenpjCKO: embryonic day 15.5; Cenpjtm1c(EUCOMM)Wtsi/Cenpjtm1c(EUCOMM)Wtsi, Emx1tm1(cre)Krj/Emx1+ (more )
Note: Conditional mutant. Double labeled: red - Sox2; green - Eomes (assay MGI:7547344).
Structure Level Pattern Image Note
TS23: cerebral cortex Weak 4F CenpjCKO Merge (left) , 4F CenpjCKO Sox2 Expression decreased compared to wild type.
Specimen 5F SOX2 Cenpj+/+: postnatal adult (more )
Structure Level Pattern Image Note
TS28: brain subventricular zone Present Regionally restricted 5F Cenpj+/+ Expression in type C cells.
TS28: brain ventricular layer Present Regionally restricted 5F Cenpj+/+ Expression in type C cells.
Specimen 5F SOX2 CenpjCKO: postnatal adult; Gt(ROSA)26Sortm1.1(Sstr3/GFP)Bky/Gt(ROSA)26Sor+ (more )
Structure Level Pattern Image Note
TS28: brain subventricular zone Weak 5F CenpjCKO Expression in fewer cells compared to control.
TS28: brain ventricular layer Weak 5F CenpjCKO Expression in fewer cells compared to control.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/14/2024
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