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Gene Expression Data
Assay Details
Assay
Reference: J:314897 Xie Q, et al., Regulation of c-Maf and alphaA-Crystallin in Ocular Lens by Fibroblast Growth Factor Signaling. J Biol Chem. 2016 Feb 19;291(8):3947-58
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7545121
Gene symbol: Maf
Gene name: MAF bZIP transcription factor
Antibody: anti-c-Maf (A300-613A)
Detection system: Secondary antibody coupled to Alexa Fluor 568
Assay notes: Another antibody was mentioned in the paper. It was not sure which one was used.
Results
Specimen 4 E10.5: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: lens vesicle Present 4_c-Maf E10.5
Specimen 4 E11.5: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: lens vesicle Present Regionally restricted 4_c-Maf E11.5 Expressed in the posterior part.
Specimen 4 E12.5: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: lens vesicle Present 4_c-Maf E12.5 Expressed in differentiating primary lens fibers.
Specimen 4 E14.5: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: lens fiber Strong 4_c-Maf E14.5 Expressed in differentiating primary and secondary lens fibers.
Specimen 7A E12.5 control: embryonic day 12.5; Mapk1tm2Moga/Mapk1tm2Moga, Mapk3tm1Gpg/Mapk3tm1Gpg (more )
Structure Level Pattern Image Note
TS20: lens vesicle Strong 7A c-Maf E12.5 Erk1-/-;Erk2fl/fl
Specimen 7A E12.5 DcKO: embryonic day 12.5; Mapk1tm2Moga/Mapk1tm2Moga, Mapk3tm1Gpg/Mapk3tm1Gpg, Tg(Pax6-cre,GFP)1Pgr/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS20: lens vesicle Present 7A c-Maf E12.5 Erk1-/-;Erk2fl/fl;Le-Cre Significantly reduced expression compared with the control.
Specimen 7A E13.5 control: embryonic day 13.5; Mapk1tm2Moga/Mapk1tm2Moga, Mapk3tm1Gpg/Mapk3tm1Gpg (more )
Structure Level Pattern Image Note
TS21: lens fiber Strong 7A c-Maf E13.5 Erk1-/-;Erk2fl/fl
Specimen 7A E13.5 DcKO: embryonic day 13.5; Mapk1tm2Moga/Mapk1tm2Moga, Mapk3tm1Gpg/Mapk3tm1Gpg, Tg(Pax6-cre,GFP)1Pgr/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS21: lens fiber Present 7A c-Maf E13.5 Erk1-/-;Erk2fl/fl;Le-Cre Significantly reduced expression compared with the control.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/21/2024
MGI 6.23 		The Jackson Laboratory