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Gene Expression Data
Assay Details
Assay
Reference: J:293326 Martis RM, et al., Mapping of the cystine-glutamate exchanger in the mouse eye: a role for xCT in controlling extracellular redox balance. Histochem Cell Biol. 2019 Oct;152(4):293-310
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7538908
Gene symbol: Slc3a2
Gene name: solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2
Antibody: anti-4F2hc
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 3c: postnatal week 3-6 (more )
Structure Level Pattern Image Note
TS28: retina ganglion cell layer Strong 3c
TS28: retina inner nuclear layer Strong 3c
TS28: retina outer plexiform layer Strong 3c
Specimen 3d: postnatal week 3-6; Slc7a11tm1Hsat/Slc7a11tm1Hsat (more )
Structure Level Pattern Image Note
TS28: retina ganglion cell layer Present 3d
TS28: retina inner nuclear layer Present 3d
TS28: retina outer plexiform layer Present 3d
Specimen 4c: postnatal week 3-6 (more )
Structure Level Pattern Image Note
TS28: ciliary epithelium Present 4c
Specimen 4d: postnatal week 3-6; Slc7a11tm1Hsat/Slc7a11tm1Hsat (more )
Structure Level Pattern Image Note
TS28: ciliary epithelium Present 4d Expression in this mutant is the same as in wild-type.
Specimen 5c: postnatal week 3-6 (more )
Note: Fixative was 0.75% paraformaldehyde.
Structure Level Pattern Image Note
TS28: iris Present Regionally restricted 5c Expression is in the anterior membrane.
TS28: iris epithelium Present Regionally restricted 5c Expression is in the posterior pigment epithelium.
Specimen 5d: postnatal week 3-6; Slc7a11tm1Hsat/Slc7a11tm1Hsat (more )
Note: Fixative was 0.75% paraformaldehyde.
Structure Level Pattern Image Note
TS28: iris Present Regionally restricted 5d Expression is in the anterior membrane and is the same as in wild-type.
TS28: iris epithelium Present Regionally restricted 5d Expression is in the posterior pigment epithelium and is the same as in wild-type.
Specimen 6f: postnatal week 3-6 (more )
Note: Fixative was 0.75% paraformaldehyde.
Structure Level Pattern Image Note
TS28: cornea epithelium Present Regionally restricted 6f Expression is in the epithelium of the peripheral and central cornea.
TS28: cornea endothelium Present 6f
TS28: cornea stroma Present 6f
Specimen 6g: postnatal week 3-6 (more )
Note: Fixative was 0.75% paraformaldehyde.
Structure Level Pattern Image Note
TS28: cornea epithelium Present Regionally restricted 6g Expression is in the epithelium of the peripheral and central cornea.
TS28: cornea endothelium Present 6g
TS28: cornea stroma Present 6g
Specimen 6h: postnatal week 3-6; Slc7a11tm1Hsat/Slc7a11tm1Hsat (more )
Note: Fixative was 0.75% paraformaldehyde.
Structure Level Pattern Image Note
TS28: cornea endothelium Present 6h Expression in this mutant is the same as in wild-type.
TS28: cornea epithelium Present 6h Expression in this mutant is the same as in wild-type.
TS28: cornea stroma Present 6h Expression in this mutant is the same as in wild-type.
Specimen 6i: postnatal week 3-6; Slc7a11tm1Hsat/Slc7a11tm1Hsat (more )
Note: Fixative was 0.75% paraformaldehyde.
Structure Level Pattern Image Note
TS28: cornea endothelium Present 6i Expression in this mutant is the same as in wild-type.
TS28: cornea epithelium Present 6i Expression in this mutant is the same as in wild-type.
TS28: cornea stroma Present 6i Expression in this mutant is the same as in wild-type.
Specimen 7h: postnatal week 3-6 (more )
Note: Double labeled: green - Slc7a11; red - wheat germ agglutinin.
Structure Level Pattern Image Note
TS28: lens epithelium Present Regionally restricted 7h Expression is in the epithelial and cortical fiber cells of the lens.
TS28: lens fiber Present Regionally restricted 7h Expression is in the epithelial and cortical fiber cells of the lens.
Specimen 7i: postnatal week 3-6 (more )
Note: Double labeled: green - Slc7a11; red - wheat germ agglutinin.
Structure Level Pattern Image Note
TS28: lens fiber Present Regionally restricted 7i Expression is in the cortical fiber cells of the lens.
Specimen 7j: postnatal week 3-6 (more )
Note: Double labeled: green - Slc7a11; red - wheat germ agglutinin.
Structure Level Pattern Image Note
TS28: lens fiber Present Regionally restricted 7j Expression is in the cortical fiber cells of the lens. Expression is absent in the core.
Specimen 7k: postnatal week 3-6; Slc7a11tm1Hsat/Slc7a11tm1Hsat (more )
Note: Double labeled: green - Slc7a11; red - wheat germ agglutinin.
Structure Level Pattern Image Note
TS28: lens epithelium Present Regionally restricted 7k Expression in this mutant is the same as in wild-type.
TS28: lens fiber Present Regionally restricted 7k Expression in this mutant is the same as in wild-type.
Specimen 7l: postnatal week 3-6; Slc7a11tm1Hsat/Slc7a11tm1Hsat (more )
Note: Double labeled: green - Slc7a11; red - wheat germ agglutinin.
Structure Level Pattern Image Note
TS28: lens fiber Present Regionally restricted 7l Expression in this mutant is the same as in wild-type.
Specimen 7m: postnatal week 3-6; Slc7a11tm1Hsat/Slc7a11tm1Hsat (more )
Note: Double labeled: green - Slc7a11; red - wheat germ agglutinin.
Structure Level Pattern Image Note
TS28: lens fiber Present Regionally restricted 7m Expression in this mutant is the same as in wild-type.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
05/28/2024
MGI 6.13 		The Jackson Laboratory