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Gene Expression Data
Assay Details
Assay
Reference: J:206632 Roberts JM, et al., Splicing factor TRA2B is required for neural progenitor survival. J Comp Neurol. 2014 Feb 1;522(2):372-92
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7531498
Gene symbol: Tra2b
Gene name: transformer 2 beta
Antibody: anti-TRA2B
Results
Specimen 2A: embryonic day 11.5 (more )
Note: 2 Double labeled: green - Tra2b; magenta - Sox2 (assay MGI:7531499).
Structure Level Pattern Image Note
TS19: brain Present Widespread 2A
TS19: telencephalon Strong Regionally restricted 2A Robust expression in cerebral cortex.

Specimen 2B/C: embryonic day 11.5 (more )
Note: Double labeled: green - Tra2b; magenta - Sox2 (assay MGI:7531499).
Structure Cell Type Level Pattern Image Note
TS19: telencephalon ventricular layer radial glial cell Present Regionally restricted 2C , 2B Expression in ventricular zone in most Sox2-expressing radial glial cells.
TS19: telencephalon Present Regionally restricted 2C , 2B Expression in preplate

Specimen 2E: embryonic day 15.5 (more )
Note: Double labeled: green - Tra2b; magenta - Sox2 (assay MGI:7531499).
Structure Level Pattern Image Note
TS23: brain Present Widespread 2E Expression throughout brain.
TS23: cerebral cortex Strong 2E Robust expression in cerebral cortex.

Specimen 2F/G: embryonic day 15.5 (more )
Note: Double labeled: green - Tra2b; magenta - Sox2 (assay MGI:7531499).
Structure Cell Type Level Pattern Image Note
TS23: cerebral cortex ventricular layer radial glial cell Present Regionally restricted 2G , 2F Expression in ventricular zone in most Sox2-expressing radial glial cells.
TS23: cortical plate Present 2F , 2G

Specimen 2I: postnatal day 0 (more )
Note: Double labeled: green - Tra2b; magenta - Sox2 (assay MGI:7531499).
Structure Level Pattern Image Note
TS27: brain Present Widespread 2I Expression throughout brain.
TS27: cerebral cortex Strong Regionally restricted 2I Robust expression in cerebral cortex.

Specimen 2J/K: postnatal day 0 (more )
Note: Double labeled: green - Tra2b; magenta - Sox2 (assay MGI:7531499).
Structure Cell Type Level Pattern Image Note
TS27: cerebral cortex ventricular zone radial glial cell Present 2K , 2J Expression in ventricular zone in most Sox2-expressing radial glial cells.
TS27: cortical plate Present 2J , 2K

Specimen 2M/N: postnatal day 0 (more )
Note: Double labeled: green - Tra2b; magenta - Bcl11b (assay MGI:7531500).
Structure Cell Type Level Pattern Image Note
TS27: cortical layer V pyramidal neuron Present 2N , 2M Expression in Bcl11b-expressing projection neurons. in cortical layers 5 and 6.
TS27: cortical layer VI pyramidal neuron Present 2N , 2M Expression in Bcl11b-expressing projection neurons. in cortical layers 5 and 6.

Specimen 2P/Q: postnatal day 0 (more )
Note: Double labeled: green - Tra2b; magenta - Bhlhe22 (assay MGI:7531501).
Structure Cell Type Level Pattern Image Note
TS27: cortical layer II pyramidal neuron Present 2P , 2Q Expression in Bhlhe22-expressing projection neurons. in cortical layers 2-5.
TS27: cortical layer III pyramidal neuron Present 2P , 2Q Expression in Bhlhe22-expressing projection neurons. in cortical layers 2-5.
TS27: cortical layer IV pyramidal neuron Present 2P , 2Q Expression in Bhlhe22-expressing projection neurons. in cortical layers 2-5.
TS27: cortical layer V pyramidal neuron Present 2P , 2Q Expression in Bhlhe22-expressing projection neurons. in cortical layers 2-5.

Specimen 5A/B: embryonic day 11.5; Emx1tm1(cre)Krj/Emx1+, Tra2btm1.1Bwir/Tra2b+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS19: telencephalon Present Regionally restricted 5B , 5A Expression in cerebral cortex.

Specimen 5C/D: embryonic day 11.5; Emx1tm1(cre)Krj/Emx1+, Tra2btm1.1Bwir/Tra2btm1.1Bwir (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS19: telencephalon Weak 5D , 5C Expression in reduced compared to control.

Specimen 5E/F: postnatal day 0; Emx1tm1(cre)Krj/Emx1+, Tra2btm1.1Bwir/Tra2b+ (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS27: cerebral cortex cerebral cortex neuron Present 5E , 5F

Specimen 5G/H: postnatal day 0; Emx1tm1(cre)Krj/Emx1+, Tra2btm1.1Bwir/Tra2btm1.1Bwir (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS27: cerebral cortex cerebral cortex neuron Weak Regionally restricted 5H , 5G Expression reduced compared to control, but present in many cells in remaining cortex.


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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory