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Gene Expression Data
Assay Details
Assay
Reference: J:183829 Correa SM, et al., Sex reversal in C57BL/6J XY mice caused by increased expression of ovarian genes and insufficient activation of the testis determining pathway. PLoS Genet. 2012 Apr;8(4):e1002569
Assay type: RT-PCR
MGI Accession ID: MGI:7524602
Gene symbol: Sostdc1
Gene name: sclerostin domain containing 1
Probe: Sostdc1-pA, Sostdc1-pB
Probe preparation: labelled with SYBR green
Assay notes: Quantitative RT-PCR. Data was summarized in Table 3.
Results
 Sample Information Bands Other Sample Information
Lane AgeStructure Size Not Specified Amount Genetic BackgroundMutant Allele(s)Sex Note
E14 Wt1+/+ XY AKR E14.0 TS22: testis Present Not Specified B6.Cg-Chr YAKR/J Male
E14 Wt1+/- XY AKR E14.0 TS22: ovary Present (a) Not Specified B6.Cg-Wt1tm1Jae Chr YAKR/J Wt1tm1Jae/Wt1+Not Specified Only mutant gonads lacking any testicular cords (classified as ovaries) were used.
E12 Sf1+/+ XY AKR E12.0 TS20: gonad
TS20: mesonephros
Present Not Specified B6.Cg-Chr YAKR/J Male Gonad-mesonephros complexes were used.
E12 Sf1+/- XY AKR E12.0 TS20: gonad
TS20: mesonephros
Present (b) Not Specified B6.Cg-Nr5a1tm1Klp Chr YAKR/J Nr5a1tm1Klp/Nr5a1+Male Gonad-mesonephros complexes were used.
E14 Sf1+/+ XY AKR E14.0 TS22: testis Present Not Specified B6.Cg-Chr YAKR/J Male
E14 Sf1+/- XY AKR E14.0 TS22: ovary Present (c) Not Specified B6.Cg-Nr5a1tm1Klp Chr YAKR/J Nr5a1tm1Klp/Nr5a1+Not Specified Only mutant gonads lacking any testicular cords (classified as ovaries) were used.
Notes:
(a) Decreased expression (4.7 fold) compared with the control.
(b) Increased expression (2.4 fold) compared with the control.
(c) Decreased expression (8.2 fold) compared with the control.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory