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Gene Expression Data
Assay Details
Assay
Reference: J:339398 Vincent E, et al., Ret deficiency decreases neural crest progenitor proliferation and restricts fate potential during enteric nervous system development. Proc Natl Acad Sci U S A. 2023 Aug 22;120(34):e2211986120
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7524012
Gene symbol: Gfra2
Gene name: glial cell line derived neurotrophic factor family receptor alpha 2
Results
Specimen 3G CFP/+ GFRA2: embryonic day 12.5; Rettm2.1Heno/Ret+ (more )
Note: Double labeled: magenta - Gfra2; green - Ret reporter (assay MGI:7523998).
Structure Level Pattern Image Note
TS20: stomach Absent 3G CFP/+ (merged) , 3G CFP/+ GFRA2
Specimen 3G CFP/CFP GFRA2: embryonic day 12.5; Rettm2.1Heno/Rettm2.1Heno (more )
Note: Double labeled: magenta - Gfra2; green - Ret reporter (assay MGI:7523998).
Structure Level Pattern Image Note
TS20: stomach Present Regionally restricted 3G CFP/CFP GFRA2 , 3G CFP/CFP (merged) Co expression with CFP restricted to cells along extrinsically innervating nerve fibers.
Specimen 3H CFP/+ GFRA2: embryonic day 14.5; Rettm2.1Heno/Ret+ (more )
Note: Double labeled: magenta - Gfra2; green - Ret reporter (assay MGI:7523998).
Structure Level Pattern Image Note
TS22: stomach Absent 3H CFP/+ (merged) , 3H CFP/+ GFRA2
Specimen CFP/CFP hindgut not shown: embryonic day 14.5; Rettm2.1Heno/Rettm2.1Heno (more )
Structure Level Pattern Image Note
TS22: hindgut Absent
Specimen 3H CFP/CFP GFRA2: embryonic day 14.5; Rettm2.1Heno/Rettm2.1Heno (more )
Note: Double labeled: magenta - Gfra2; green - Ret reporter (assay MGI:7523998).
Structure Level Pattern Image Note
TS22: stomach Present Regionally restricted 3H CFP/CFP GFRA2 , 3H CFP/CFP (merged) Co-expression with CFP restricted to cells along extrinsically innervating nerve fibers.
Specimen S7D CFP/+ GFRA2: embryonic day 12.5; Rettm2.1Heno/Ret+ (more )
Note: Double labeled: magenta - Gfra2; green - Ret reporter (assay MGI:7523998).
Structure Level Pattern Image Note
TS20: esophagus Present Regionally restricted S7D CFP/+ (merged) , S7D CFP/+ GFRA2 Co-expression with CFP in putative branch B cells in both genotypes. Expression in maturing branch B cells.
Specimen S7D CFP/CFP GFRA2: embryonic day 12.5; Rettm2.1Heno/Rettm2.1Heno (more )
Note: Double labeled: magenta - Gfra2; green - Ret reporter (assay MGI:7523998).
Structure Level Pattern Image Note
TS20: esophagus Present Regionally restricted S7D CFP/CFP (merged) , S7D CFP/CFP GFRA2 Co-expression with CFP in putative branch B cells in both genotypes. Expression in maturing branch B cells.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory