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Gene Expression Data
Assay Details
Assay
Reference: J:92061 Eng SR, et al., Coordinated regulation of gene expression by Brn3a in developing sensory ganglia. Development. 2004 Aug;131(16):3859-70
Assay type: RNA in situ
MGI Accession ID: MGI:7521938
Gene symbol: Htr3a
Gene name: 5-hydroxytryptamine (serotonin) receptor 3A
Probe: 5HT3R probe
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 2C 5HT3R +/+: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: glossopharyngeal ganglion Present 2C 5HT3R +/+
TS21: trigeminal ganglion Present 2C 5HT3R +/+
TS21: vagus ganglion Present 2C 5HT3R +/+
Specimen 5HT3R +/+ not shown: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: dorsal root ganglion Present
TS21: vestibulo-cochlear ganglion Present
Specimen 2C 5HT3R -/-: embryonic day 13.5; Pou4f1tm1Nat/Pou4f1tm1Nat (more )
Structure Level Pattern Image Note
TS21: glossopharyngeal ganglion Strong 2C 5HT3R -/- Markedly increased expression in trigeminal ganglion and IX/X ganglion.
TS21: trigeminal ganglion Strong 2C 5HT3R -/- Markedly increased expression in trigeminal ganglion and IX/X ganglion.
TS21: vagus ganglion Strong 2C 5HT3R -/- Markedly increased expression in trigeminal ganglion and IX/X ganglion.
Specimen 5HT3R -/- not shown: embryonic day 13.5; Pou4f1tm1Nat/Pou4f1tm1Nat (more )
Structure Level Pattern Image Note
TS21: vestibulo-cochlear ganglion Present Expression in vestibulocochlear ganglion not increased.
TS21: dorsal root ganglion Strong Markedly increased expression in dorsal root ganglion.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory