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Gene Expression Data
Assay Details
Assay
Reference: J:58028 Russo MA, et al., Spatiotemporal patterns of expression of neurotrophins and neurotrophin receptors in mice suggest functional roles in testicular and epididymal morphogenesis. Biol Reprod. 1999 Oct;61(4):1123-32
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7519007
Gene symbol: Ntf3
Gene name: neurotrophin 3
Antibody: anti-NT-3 (sc-547)
Detection system: Secondary antibody
Results
Specimen 3A: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: interstitium of the testis Strong Regionally restricted 3A First expression in mesenchymal cells at 14.5 dpc. High levels of expression during fetal development. Expression in cytoplasm of peritubular mesenchymal cells.

Specimen 3B: postnatal day 1 (more )
Structure Level Pattern Image Note
TS27: interstitium of the testis Strong Widespread 3B Expression in cytoplasm of peritubular mesenchymal cells. Intense expression in most interstitial cells at birth. Strongest expression in newborn (P1).

Specimen 3C: postnatal day 20 (more )
Structure Level Pattern Image Note
TS28: interstitium of the testis Trace Single cells 3C Expression in cytoplasm of peritubular mesenchymal cells. Expression gradually decreased postnally. Expression confined to only a few peritubular cells.

Specimen adult testis not shown: postnatal adult (more )
Structure Level Pattern Image Note
TS28: testis Absent Expression disappeared in adult testis.

Specimen E14.5 not shown: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: male reproductive system mesenchyme Present Regionally restricted Expression in mesenchymal cells of developing epididymis. Expression uniformly distributed in intertubular compartment.

Specimen 3E: postnatal day 1 (more )
Structure Level Pattern Image Note
TS27: epididymis Present Regionally restricted 3E Diffuse expression in intersitital cells. Maximal expression duting neonatal period.

Specimen 3F: postnatal day 20 (more )
Structure Level Pattern Image Note
TS28: epididymis Weak Regionally restricted 3F Expression gradually decreases towards pubety. Expression restricted to a few layers of concentrically arranged cells surrounding epididymal duct.

Specimen adult epididymis not shown: postnatal adult (more )
Structure Level Pattern Image Note
TS28: epididymis Absent Expression disappeared in adult epididymis.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/14/2024
MGI 6.23
The Jackson Laboratory