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Gene Expression Data
Assay Details
Assay
Reference: J:281257 Witteveen JS, et al., Haploinsufficiency of MeCP2-interacting transcriptional co-repressor SIN3A causes mild intellectual disability by affecting the development of cortical integrity. Nat Genet. 2016 Aug;48(8):877-87
Assay type: RT-PCR
MGI Accession ID: MGI:7514843
Gene symbol: Sin3a
Gene name: transcriptional regulator, SIN3A (yeast)
Probe: MmSin3a-Primer set 1
Probe preparation: labelled with SYBR green
Assay notes: Quantitative RT-PCR. Relative expression was normalized to Ppia and Actb. The authors did not specify which primer set was used, MmSin3a-Primer set 2 MGI:7514838 may have been used instead.
Results Image: 2c S1
 Sample Information Bands Other Sample Information
Lane AgeStructure Size Not Specified Amount Genetic BackgroundMutant Allele(s)Sex Note
E16.5 E16.5 TS24: neocortex region Present 1.5 µg; total RNA C57BL/6JOlaHsd Not Specified primary somatosensory cortex
E18.5 E18.5 TS26: parietal cortex Present 1.5 µg; total RNA C57BL/6JOlaHsd Not Specified primary somatosensory cortex
P7 P7 TS28: primary somatosensory cortex Present (a) 1.5 µg; total RNA C57BL/6JOlaHsd Not Specified
P14 P14 TS28: primary somatosensory cortex Present 1.5 µg; total RNA C57BL/6JOlaHsd Not Specified
P21 P21 TS28: primary somatosensory cortex Present 1.5 µg; total RNA C57BL/6JOlaHsd Not Specified
P60 P60 TS28: primary somatosensory cortex Present (b) 1.5 µg; total RNA C57BL/6JOlaHsd Not Specified
Notes:
(a) There is a gradual decrease in expression from E16.5.
(b) There is a gradual increase in expression from P7.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/07/2024
MGI 6.23 		The Jackson Laboratory