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Gene Expression Data
Assay Details
Assay
Reference: J:221937 Watson JA, et al., Motor and Sensory Deficits in the teetering Mice Result from Mutation of the ESCRT Component HGS. PLoS Genet. 2015 Jun;11(6):e1005290
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7510018
Gene symbol: Hgs
Gene name: HGF-regulated tyrosine kinase substrate
Antibody: anti-HRS
Detection system: Secondary antibody coupled to Alexa Fluor 568
Results
Specimen 6 HGS (upper): postnatal week 4 (more )
Note: Double labeled: red - Hgs; green - neurofilament.
Structure Level Pattern Image Note
TS28: sciatic nerve Present Regionally restricted 6_Overlay (upper) , 6_HGS (upper) Expression did not overlap with neurofilament staining in axons.
Specimen 6 HGS (lower): postnatal week 4 (more )
Note: Double labeled: red - Hgs; green - S100b (assay MGI:7510019).
Structure Cell Type Level Pattern Image Note
TS28: sciatic nerve Schwann cell Present Regionally restricted 6_Overlay (lower) , 6_HGS (lower) Expression localized to external boundary of Schwann cell body.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/30/2024
MGI 6.23 		The Jackson Laboratory