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Gene Expression Data
Assay Details
Assay
Reference: J:324832 Sun Y, et al., Single-cell transcriptomic landscapes of the otic neuronal lineage at multiple early embryonic ages. Cell Rep. 2022 Mar 22;38(12):110542
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:7493750
Gene symbol: Myt1
Gene name: myelin transcription factor 1
Reporter: GFP
Antibody: anti-GFP (ab13970)
Detection system: Secondary antibody
Results
Specimen 4E: embryonic day 12.5; Gt(ROSA)26Sortm9(CAG-tdTomato)Hze/Gt(ROSA)26Sor+, Myt1tm1(EGFP/icre)Ldh/Myt1+ (more )
Note: Conditional mutant. Triple labeled: green - Myt1; red - Cre reporter; blue - Hoechst.
Structure Level Pattern Image Note
TS21: cochlear ganglion Present 4E'' , 4E
TS21: vestibular ganglion Present 4E'' , 4E
Specimen 4F: embryonic day 12.5; Gt(ROSA)26Sortm9(CAG-tdTomato)Hze/Gt(ROSA)26Sor+, Myt1tm1(EGFP/icre)Ldh/Myt1+ (more )
Note: Conditional mutant. Multi-labeled: green - Myt1 reporter; white - Sox2 (assay MGI:7493756); red - Cre reporter; blue - Hoechst.
Structure Cell Type Level Pattern Image Note
TS21: cochlear ganglion neuron Present 4F''' , 4F
TS21: cochlear ganglion glial cell Absent 4F''' , 4F
Specimen S3E: embryonic day 15.5; Myt1tm1(EGFP/icre)Ldh/Myt1tm1(EGFP/icre)Ldh (more )
Note: Triple labeled: green - Myt1 reporter; red - Myt1 protein (assay MGI:7493605); blue - Hoechst.
Structure Cell Type Level Pattern Image Note
TS23: cochlear ganglion spiral ganglion neuron Present S3E'' , S3E , S3F , S3F''
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/23/2024
MGI 6.23 		The Jackson Laboratory