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Gene Expression Data
Assay Details
Assay
Reference: J:256230 Shin SW, et al., Cytoplasmic cleavage of DPPA3 is required for intracellular trafficking and cleavage-stage development in mice. Nat Commun. 2017 Nov 21;8(1):1643
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7482802
Gene symbol: Rab7
Gene name: RAB7, member RAS oncogene family
Antibody: anti-RAB7 [E{R7589] (ab137029)
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 4a RAB7: embryonic day 0.5 (more )
Note: Double labeled: green - Rab7; red - phalloidin.
Structure Level Pattern Image Note
TS1: 1-cell stage embryo Present Punctate 4a RAB7 Merge , 4a RAB7 Punctate expression in periphery of cytoplasm near plasma membrane.
Specimen 4b RAB7: embryonic day 0.5; Dppa3tm1Masu/Dppa3tm1Masu (more )
Note: Embryos resulting from mating of Dppa3 KO females with WT males. Double labeled: green - Rab7; red - phalloidin.
Structure Level Pattern Image Note
TS1: 1-cell stage embryo Present Regionally restricted 4b RAB7 , 4b RAB7 Merge Expression abnormally aggregated in cytoplasm, colocalized with actin.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/23/2024
MGI 6.23 		The Jackson Laboratory