Gene Expression Data
Assay Details
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Assay
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Reference:
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J:126484
Luo W, et al., A hierarchical NGF signaling cascade controls Ret-dependent and Ret-independent events during development of nonpeptidergic DRG neurons. Neuron. 2007 Jun 7;54(5):739-54
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Assay type:
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RNA in situ
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MGI Accession ID:
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MGI:7481273
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Gene symbol:
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Gfra2
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Gene name:
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glial cell line derived neurotrophic factor family receptor alpha 2
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Probe:
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Gfra2 probe
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Probe preparation:
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labelled with digoxigenin RNA
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Results
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Specimen
S1E:
embryonic day 12.0
(more  )
Specimen
S1E:
(close  )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 12.0
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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| Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
| TS20: dorsal root ganglion |
sensory neuron of dorsal root ganglion |
Present |
Regionally restricted |
S1E
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Expression in few large diameter neurons at E12 and E16.
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Specimen
S1F:
embryonic day 16.0
(more )
Specimen
S1F:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 16.0
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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| Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
| TS24: dorsal root ganglion |
sensory neuron of dorsal root ganglion |
Present |
Regionally restricted |
S1F
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Expression in few large diameter neurons at E12 and E16.
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Specimen
S1G:
postnatal day 0
(more )
Specimen
S1G:
(close )
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Genetic Background:
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Not Specified
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Age:
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postnatal day 0
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Sex:
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Not Specified
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Type:
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section
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| Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
| TS27: dorsal root ganglion |
sensory neuron of dorsal root ganglion |
Present |
Regionally restricted |
S1G
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Expression in small to mediam diameter neurons initiated from P0.
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Specimen
S1H:
postnatal day 10
(more )
Specimen
S1H:
(close )
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Genetic Background:
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Not Specified
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Age:
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postnatal day 10
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Sex:
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Not Specified
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Type:
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section
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| Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
| TS28: dorsal root ganglion |
sensory neuron of dorsal root ganglion |
Strong |
Regionally restricted |
S1H
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Expression in neuronss increases dramatically after birth. Number of expressing cells increases between P0 to P10.
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Specimen
2E:
(close )
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Genetic Background:
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involves: 129S7/SvEvBrd * 129X1/SvJ
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Mutant Allele(s):
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Baxtm1Sjk/Baxtm1Sjk
Ngftm1Gne/Ngf+
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Age:
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postnatal day 0
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Sex:
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Not Specified
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Type:
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section
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| Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
| TS27: dorsal root ganglion |
sensory neuron of dorsal root ganglion |
Weak |
Regionally restricted |
2E
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Weak expression at P0. Expression in 17.8% of neurons.
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Specimen
2F:
(close )
| Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
| TS27: dorsal root ganglion |
sensory neuron of dorsal root ganglion |
Trace |
Regionally restricted |
2F
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Expression dramatically reduced to 9.0% of neurons.
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Specimen
5C:
(close )
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Genetic Background:
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involves: 129 * C57BL/6
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Mutant Allele(s):
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Rettm1Ddg/Rettm1Ddg
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Age:
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postnatal day 10
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Sex:
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Not Specified
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Type:
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section
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| Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
| TS28: dorsal root ganglion |
sensory neuron of dorsal root ganglion |
Present |
Regionally restricted |
5C
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Expression increases postnatally. Expression in ~78 neurons/section.
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Specimen
5D:
(close )
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Genetic Background:
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involves: 129 * C57BL/6 * C57BL/6J * CBA/J
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Mutant Allele(s):
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Rettm1Ddg/Rettm1Ddg
H2az2Tg(Wnt1-cre)11Rth/H2az2+
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Age:
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postnatal day 10
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Sex:
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Not Specified
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Type:
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section
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Note:
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Conditional mutant.
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| Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
| TS28: dorsal root ganglion |
sensory neuron of dorsal root ganglion |
Weak |
Regionally restricted |
5D
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Significant reduction in number of expressing cells. Expression in ~50 neurons/section.
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Specimen
S6C:
(close )
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Genetic Background:
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involves: 129 * C57BL/6
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Mutant Allele(s):
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Rettm1Ddg/Rettm1Ddg
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Age:
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postnatal day 2
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Sex:
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Not Specified
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Type:
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section
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Specimen
S6D:
(close )
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Genetic Background:
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involves: 129 * C57BL/6 * C57BL/6J * CBA/J
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Mutant Allele(s):
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Rettm1Ddg/Rettm1Ddg
H2az2Tg(Wnt1-cre)11Rth/H2az2+
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Age:
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postnatal day 2
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Sex:
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Not Specified
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Type:
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section
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Note:
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Conditional mutant.
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| Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
| TS27: dorsal root ganglion |
sensory neuron of dorsal root ganglion |
Present |
Regionally restricted |
S6D
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Weak expression in Gfra2 expressing neurons. Overlap with Ret expression in 13.9% of cells.
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