Mllt11 RNA in situ Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:324710 Stanton-Turcotte D, et al., Mllt11 Regulates Migration and Neurite Outgrowth of Cortical Projection Neurons during Development. J Neurosci. 2022 May 11;42(19):3931-3948
Assay type:	RNA in situ
MGI Accession ID:	MGI:7470827
Gene symbol:	Mllt11
Gene name:	myeloid/lymphoid or mixed-lineage leukemia; translocated to, 11

Probe:	Mllt11 cDNA
Probe preparation:	Antisense RNA

Results

E1-1C P7 Cortex ©

Specimen E1-1 P7 Cortex: postnatal day 7 (more

)

Structure	Level	Pattern	Image	Note
TS28: cerebral cortex	Present		E1-1C P7 Cortex

E1-1C P7 Hippocampus ©

Specimen E1-1 P7 Hippocampus: postnatal day 7 (more

)

Structure	Level	Pattern	Image	Note
TS28: hippocampus	Present		E1-1C P7 Hippocampus

E1-1C P14 Cortex ©

Specimen E1-1 P14 Cortex: postnatal day 14 (more

)

Structure	Level	Pattern	Image	Note
TS28: cerebral cortex	Present		E1-1C P14 Cortex

E1-1C P14 Hippocampus ©

Specimen E1-1 P14 Hippocampus: postnatal day 14 (more

)

Structure	Level	Pattern	Image	Note
TS28: hippocampus	Present		E1-1C P14 Hippocampus	Expression decreased progressively.

E1-1C P21 Cortex ©

Specimen E1-1 P21 Cortex: postnatal day 21 (more

)

Structure	Level	Pattern	Image	Note
TS28: cerebral cortex	Present		E1-1C P21 Cortex	Expression was maintained until P21.

E1-1C P21 Hippocampus ©

Specimen E1-1 P21 Hippocampus: postnatal day 21 (more

)

Structure	Level	Pattern	Image	Note
TS28: hippocampus	Present		E1-1C P21 Hippocampus	Expression decreased progressively.

E1-1C P28 Cortex ©

Specimen E1-1 P28 Cortex: postnatal day 28 (more

)

Structure	Level	Pattern	Image	Note
TS28: hippocampus	Ambiguous		E1-1C P28 Cortex	Expression levels were indistinguishable from background.

E1-1C P28 Hippocampus ©

Specimen E1-1 P28 Hippocampus: postnatal day 28 (more

)

Structure	Level	Pattern	Image	Note
TS28: hippocampus	Weak		E1-1C P28 Hippocampus

E-1-2C Ctrl ©

Specimen E1-2C Ctrl: postnatal day 7 (more

)

Structure	Level	Pattern	Image	Note
TS28: cerebral cortex	Present		E-1-2C Ctrl

E-1-2C cKO ©

Specimen E1-2C cKO: postnatal day 7; Mllt11^{tm1c(KOMP)Mbp}/Mllt11^{tm1c(KOMP)Mbp}, Gt(ROSA)26Sor^{tm9(CAG-tdTomato)Hze}/Gt(ROSA)26Sor⁺, Cux2^{tm1.1(cre)Mull}/Cux2⁺ (more

)
Note: Conditional mutant.

Structure	Level	Pattern	Image	Note
TS28: cerebral cortex	Weak	Regionally restricted	E-1-2C cKO	Decreased labeling in the superficial cortex.

E-1-2D Ctrl ©

Specimen E1-2D Ctrl: postnatal day 7 (more

)

Structure	Level	Pattern	Image	Note
TS28: hippocampus	Present		E-1-2D Ctrl

E-1-2D cKO ©

Specimen E1-2D cKO: postnatal day 7; Mllt11^{tm1c(KOMP)Mbp}/Mllt11^{tm1c(KOMP)Mbp}, Gt(ROSA)26Sor^{tm9(CAG-tdTomato)Hze}/Gt(ROSA)26Sor⁺, Cux2^{tm1.1(cre)Mull}/Cux2⁺ (more

)
Note: Conditional mutant.

Structure	Level	Pattern	Image	Note
TS28: hippocampus	Ambiguous		E-1-2D cKO	Significantly decreased expression was seen.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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