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Gene Expression Data
Assay Details
Assay
Reference: J:324710 Stanton-Turcotte D, et al., Mllt11 Regulates Migration and Neurite Outgrowth of Cortical Projection Neurons during Development. J Neurosci. 2022 May 11;42(19):3931-3948
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7470820
Gene symbol: Nefm
Gene name: neurofilament, medium polypeptide
Antibody: anti-neurofilament clone 2H3
Detection system: Secondary antibody coupled to Alexa Fluor 594
Results
Specimen 5A Ctrl: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: cerebral cortex Present Regionally restricted 5A Ctrl Expressed in the cortical white matter tracts.
Specimen 5A cKO: embryonic day 16.5; Mllt11tm1c(KOMP)Mbp/Mllt11tm1c(KOMP)Mbp, Gt(ROSA)26Sortm9(CAG-tdTomato)Hze/Gt(ROSA)26Sor+, Cux2tm1.1(cre)Mull/Cux2+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS24: cerebral cortex Present Regionally restricted 5A cKO Significant decrease in the positive fiber thickness in the cortical white matter.
Specimen 5E Ctrl: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: cerebral cortex Present Regionally restricted 5E Ctrl Expressed in the cortical white matter tracts.
Specimen 5E cKO: embryonic day 18.5; Mllt11tm1c(KOMP)Mbp/Mllt11tm1c(KOMP)Mbp, Gt(ROSA)26Sortm9(CAG-tdTomato)Hze/Gt(ROSA)26Sor+, Cux2tm1.1(cre)Mull/Cux2+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS26: cerebral cortex Present Regionally restricted 5E cKO Significant decrease in the positive fiber thickness in the cortical white matter.
Specimen 5I Rostral Ctrl: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: corpus callosum Present 5I Rostral Ctrl
Specimen 5I Rostral cKO: embryonic day 18.5; Mllt11tm1c(KOMP)Mbp/Mllt11tm1c(KOMP)Mbp, Gt(ROSA)26Sortm9(CAG-tdTomato)Hze/Gt(ROSA)26Sor+, Cux2tm1.1(cre)Mull/Cux2+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS26: corpus callosum Present 5I Rostral cKO Significantly decreased expression compared with the control.
Specimen 5I Caudal Ctrl: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: cerebral internal capsule Present 5I Caudal Ctrl
TS26: corpus callosum Present 5I Caudal Ctrl
Specimen 5I Caudal cKO: embryonic day 18.5; Mllt11tm1c(KOMP)Mbp/Mllt11tm1c(KOMP)Mbp, Gt(ROSA)26Sortm9(CAG-tdTomato)Hze/Gt(ROSA)26Sor+, Cux2tm1.1(cre)Mull/Cux2+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS26: corpus callosum Present 5I Caudal cKO Significantly decreased expression compared with the control.
TS26: cerebral internal capsule Present 5I Caudal cKO Similar as in the control.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/14/2024
MGI 6.23 		The Jackson Laboratory