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Gene Expression Data
Assay Details
Assay
Reference: J:297164 Nie X, et al., mTOR plays a pivotal role in multiple processes of enamel organ development principally through the mTORC1 pathway and in part via regulating cytoskeleton dynamics. Dev Biol. 2020 Nov 1;467(1-2):77-87
Assay type: RT-PCR
MGI Accession ID: MGI:7467228
Gene symbol: Amelx
Gene name: amelogenin, X-linked
Probe: Amelx-pF, Amelx-pR
Probe preparation: labelled with SYBR green
Assay notes: Quantitative RT-PCR. Relative expression was normalized to Gapdh.
Results
Image: 6N Amel ©

 Sample Information Bands Other Sample Information
Lane AgeStructure Size Not Specified Amount Genetic BackgroundMutant Allele(s)Sex Note
Ct P0 TS27: tooth Present Not Specified; total RNA involves: 129S4/SvJae * C57BL/6J Mtortm1.2Koz/Mtor+Not Specified
mTOR cKO P0 TS27: tooth Present (a) Not Specified; total RNA involves: 129S4/SvJae * C57BL/6 * C57BL/6J * CBA Mtortm1.2Koz/Mtortm1.2Koz, Tg(KRT14-cre)1Amc/0Not Specified Conditional mutant.
Tsc1 cKO P0 TS27: tooth Present (b) Not Specified; total RNA involves: 129S4/SvJae * C57BL/6 * C57BL/6J * CBA Tg(KRT14-cre)1Amc/0, Tsc1tm1Djk/Tsc1tm1DjkNot Specified Conditional mutant.
Notes:
(a) Significantly reduced expression in mutants compared to controls.
(b) Increased expression in mutants compared to controls.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/16/2024
MGI 6.23 		The Jackson Laboratory